经验法与预注射试验法扫描启动时间在冠状动脉CTA的应用比较  

Application of Experience Method and Pre-Injection Test Method in Determining the Scanning Start Time for Coronary CT Angiography:A Comparitive Study

作　　者：崔燕海[1] 郑君惠[1] 梁长虹[1] 黄美萍[1] 刘辉[1] 

机构地区：[1]广东省人民医院(广东省医学科学院)放射科,广州510080

出　　处：《临床放射学杂志》2015年第2期276-279,共4页Journal of Clinical Radiology

基　　金：广东省科技支撑计划项目(编号:2011B061300018);广东省医学科研基金项目(编号:B2011015)

摘　　要：目的探讨经验法与预注射试验法两种扫描启动时间对64层螺旋CT冠状动脉CTA成像的影响和临床检查效果。方法共232例可疑或诊断冠心病者进行冠状动脉CTA检查,分别采用经验法(168例)与预注射试验法(64例)确定扫描启动时间;采用相同对比剂注射方案(370 mg I/ml×4 ml/s×60 ml)进行冠状动脉CTA检查;对两组的血管强化程度和不同强化程度者分布情况进行比较。结果经验法与预注射试验法确定扫描启动时间,所得的血管平均强化水平相近,不同强化程度者分布情况相似,两组间的差异无统计学意义。结论经验法扫描启动时间能够满足64层螺旋CT冠状动脉CTA强化水平,节省对比剂用量,减轻患者碘负荷带来的负面影响,尤其对于心功能较好的筛查病例更具有积极意义。Objective To investigate the influence of scanning start time determined by the experience method and the pre-injection test method in coronary angiography with 64-slice spiral CT scanner on the imaging quality and the clinical effect, and to compare the practical usefulness of the experience method with the pre-injection test method. Methods Coronary artery CT angiography （CTA） was performed in 232 patients with suspected or confirmed coronary artery disease. The scanning start time was determined by experience method （ experience group, n = 168 ） or by pre-injection test method （pre-injection group, n =64）. The same contrast injection scheme was employed （370 mgI/ml×4 ml/s ×60 ml） in both groups to perform coronary CTA. The enhancement degree of aortic root and the distribution of patients with different en- hancement degree were estimated and the results were compared between the two groups. Results The scanning start time was determined by experience method and pre-iujection test method separately in the two groups. The mean enhance- ment degree of the aortic root was similar in the two groups, and the distribution of patients with different enhancement de- gree in the two groups was also the same. The differences between the two groups were statistically not significant. Conclu- sion The scanning start time determined by experience method can meet the requirements of enhancement level in 64-slice spiral CT coronary angiography. It can save the dosage of contrast and mitigate the negative effect brought by iodine load, and, especially, it has more advantages for screening patients with better cardiac function.

关 键 词：冠状动脉 对比剂 启动时间 体层摄影术 X线计算机 

分 类 号：R816.2[医药卫生—放射医学]