雌激素替代疗法对绝经期骨质疏松伴牙周病患者系统治疗的影响  

Therapeutic effect of hormone replacement therapy on periodontitis combined with postmenopausal osteoporosis

作　　者：姚丽[1] 黄薇[1] 刘莹[1] 

机构地区：[1]北京市和平里医院口腔科,北京100013

出　　处：《中国骨质疏松杂志》2015年第2期196-198,共3页Chinese Journal of Osteoporosis

摘　　要：目的研究雌激素替代疗法对绝经期雌激素降低伴骨质疏松女性牙周病患者进行牙周系统治疗的临床疗效。方法观察38名绝经期女性雌激素、骨密度测量水平及牙周各项指标,根据身体状况随机分为两组,对照组采取牙周系统治疗,实验组补充雌激素结合牙周系统治疗。术后3个月、6个月记录各项指标进行对比研究。结果 38名绝经期女性患者雌激素水平及骨密度存在不同程度降低,实验组12例患者补充雌激素3个月后雌激素恢复或接近正常(P<0.05),统计学上有显著性差异;6个月骨密度测量出现不同程度改善(P>0.05),但统计学上无显著性差异;附着丧失水平较未补充雌激素组降低(P>0.05),但统计学上无显著性差异。结论雌激素替代疗法可以有效提高绝经期女性雌激素、骨密度水平及牙周病患者牙周系统治疗的疗效。Objective To study the clinical effect of hormone replacement therapy on the treatment of periodontal system in postmenopausal osteoporotic women with periodontitis.Methods Estrogen level,BMD,BI,PD,and CAL of 30 periodontal patients were observed.Patients were randomly divided to 2 groups according to their physical status.Patients in control group received periodontal treatment.Patients in experiment group received periodontal treatment combined with hormone replacement therapy.Data were recorded and compared after 3-month and 6-month treatment.Results Estrogen level and BMD decreased to different extent in 38 postmenopausal osteoporotic women.Estrogen level recovered or closes to normal in 12 patients who had received hormone replacement therapy for 3 months.The difference was statistically significant（P〈0.05）.BMD improved to different extent in 6 months,with no significant difference（P〈0.05）.BI,PD,and CAL decreased compared to control group,with no significant difference（P〈0.05）.Conclusion Hormone replacement therapy can effectively improve estrogen level,BMD,and the efficacy of periodontal systemic therapy.

关 键 词：雌激素替代疗法 绝经期 雌激素 骨密度 牙周系统治疗 

分 类 号：R45[医药卫生—治疗学]