SPECT评价改良脑-硬膜-动脉血管联通术治疗烟雾病疗效  

Evaluation of effect of modified encephalo-duro-arterio-synangiosis on Moyamoya disease patients by single photon emission tomography

作　　者：赵刚[2] 钟世镇[1] 张金赫[3] 王玉宝[2] 王伟民[2] 

机构地区：[1]南方医科大学解剖教研室,广州510515 [2]广州军区广州总医院神经外科,广州510010 [3]广州军区广州总医院核医学科,广州510010

出　　处：《中华神经医学杂志》2015年第3期271-273,共3页Chinese Journal of Neuromedicine

基　　金：广东省科技计划基金（20138021800218）

摘　　要：目的 探讨单光子发射计算机断层显像术（SPECT）对评价改良脑-硬膜-动脉血管联通术（EDAS）治疗烟雾病（MMD）疗效的应用价值. 方法 广州军区广州总医院神经外科自2011年1月至2013年12月采用改良脑-硬膜-动脉血管联通术（EDAS）治疗MMD患者36例,其中缺血型MMD患者29例,出血型MMD患者7例,对患者术前及术后行单光子发射计算机断层显像术（SPECT）检查,比较手术侧大脑半球脑血流量的变化. 结果 36例MMD患者共41侧大脑半球行EDAS术,术后23侧大脑半球术后的脑血流量较术前增加,总体改善率为56.1％（23/41）,其中缺血型MMD患者中20测大脑半球术后的脑血流量较术前增加,改善率为58.8％（20/34）,出血型MMD患者中3测大脑半球术后的脑血流量较术前增加,改善率为42.9％（3/7）. 结论 改良EDAS治疗MMD术后脑组织血流量明显改善,证明改良EDAS治疗MMD疗效确切.Objective To evaluate the effects of modified encephalo-duro-arterio-synangiosis （EDAS） on Moyamoya diseases （MMD） by single photon emission tomography （SPECT）.Methods Thirty-six patients with MMD （29 with ischemic MMD and 7 with hemorrhagic MMD）,admitted to our hospital from January 2011 to December 2013 and treated by modified EDAS,were chosen in our study;all the patients were followed up by SPECT,and the images changes before and after modified EDAS were compared.Results In the 36 MMD patients,41 hemisheres were treated by modified EDAS; the total improvement rate was 56.1% （23/41）,enjoying increased cerebral blood flow after EDAS; in ischemic MMD patients,the total improvement rate was 58.8% （20/34）,while those was 42.9% （3/7） in hemorrhagic MMD patients.Conclusion The cerebral blood flow is improved obviously when MMD is treated by modified EDAS,especial on ischemic MMD patients.

关 键 词：烟雾病 改良脑-硬膜-动脉血管联通术 单光子发射计算机断层显像术 

分 类 号：R651.12[医药卫生—外科学]