啮齿目中RNase4基因的分子进化研究  

Molecular Evolution of the RNase4 Gene in Rodent

作　　者：郎大田 王磊[1] 罗家刚[1] 祁岑[1] 王忻 

机构地区：[1]昭通学院化学与生命科学学院,云南昭通657000 [2]云南省粮油科学研究院,云南昆明650033

出　　处：《云南师范大学学报（自然科学版）》2015年第2期73-78,共6页Journal of Yunnan Normal University:Natural Sciences Edition

摘　　要：RNase4基因是RNASE A基因超家族中的一个重要成员,是分子进化研究的最佳模型之一.首次在基因组水平对啮齿目中的16个物种进行RNase4基因深入分析.在白臀豚鼠、几内亚猪、鹿白足鼠和非洲跳鼠中检测到不同程度的RNase4基因扩张,并且经历了3次独立的基因复制事件.其中,在白臀豚鼠和几内亚猪中检测到1次基因复制事件;在鹿白足鼠和非洲跳鼠中发生2次基因复制事件,并且经历了"生与灭"的进化模式.RNase4gene is an important member of the RNASE A superfamily.It has been regarded as one of the key models in studies of molecular evolution.We firstly analysis RNase4 gene from 16 Rodent genomes at the genome level.Gene expansions were identified in Cavia aperea,Cavia porcellus,Peromyscus maniculatus and Jaculus jaculus.Three independent gene duplication events of the RNase4 gene were identified in the rodent.One gene duplication event was identified in Cavia apereaand Cavia porcellus.Two gene duplications events and the ＂birth and death＂evolution pattern were detected in Peromyscus maniculatus and Jaculus jaculus.

关 键 词：啮齿目 RNase4基因 分子进化 基因复制 

分 类 号：Q343.1[生物学—遗传学] Q11