早发型与晚发型新生儿败血症临床比较  

Clinical comparison of early-onset and late-onset neonatal sepsis

作　　者：王红[1] 李珊[2] 

机构地区：[1]解放军第117医院儿科,杭州310013 [2]杭州师范大学附属医院儿科,杭州310015

出　　处：《郑州大学学报（医学版）》2015年第2期283-285,共3页Journal of Zhengzhou University(Medical Sciences)

摘　　要：目的:探讨早发型与晚发型新生儿败血症的临床表现、血液检查结果及并发症发生情况的差异,为提高该病的诊断及治疗水平提供帮助。方法:选取2011年6月至2013年6月收治的新生儿败血症60例,分为早发型组和晚发型组,每组30例。对2组患儿的临床表现、血液学相关检查结果及并发症发生情况进行比较。结果:早发型组硬肿、反应迟钝发生率高于晚发型组(χ2=12.273、5.963,P均<0.05)。早发型组感染性休克、DIC发生率高于晚发型组(χ2=6.648、5.455,P均<0.05),而晚发型组化脓性脑炎发生率则高于早发型组(χ2校正=5.192,P=0.023)。早发型组PLT低于晚发型组(t=4.298,P<0.001)。结论:早发型与晚发型新生儿败血症临床表现、辅助检查各异,临床诊治过程中需综合分析。Aim：To explore the early-onset and late-onset neonatal sepsis′clinical manifestations , blood test results and complications .Methods：A total of 60 patients with neonatal sepsis were collected and divided into early-onset group （ n=30 ） and late-onset group （ n=30 ） .For all the children , clinical manifestations , hematology associated results and complications were retrospectively analyzed .Results： The rates of hard swollen and lag in response in early-onset group were significantly higher than those of late-onset group（χ2 =12.273,5.963,P〈0.05）.The rates of septic shock and DIC in early-onset group were significantly higher than those of the late-onset group（χ2 =6.648,5.455,P〈0.05）, while the suppurative encephalitis incidence rate was lower （χ2adjusted =5.192,P=0.023）.In early-onset group PLT was lower com-pared with the late-onset group（t=4.298,P〈0.001）.Conclusion：Early-onset and late-onset neonatal sepsis have dif-ferent clinical manifestations and auxiliary examination .

关 键 词：早发型 晚发型 新生儿败血症 

分 类 号：R722.131[医药卫生—儿科]