C-反应蛋白/白蛋白与脓毒性休克患者90d预后价值的研究  

The study on prognostic value of C-reactive protein/albumin ratio in 90 days mortality of septic shock patients

作　　者：王龙廷 郭凯[2] 周荣斌[2] 

机构地区：[1]山西医科大学第二临床医学院,太原030001 [2]北京军区总医院急诊科

出　　处：《临床急诊杂志》2015年第3期175-178,共4页Journal of Clinical Emergency

基　　金：首都医学发展基金联合攻关课题(No:20091026);天津市科技创新专项基金项目(No:06F22DSH00403)

摘　　要：目的:评估CRP/ALB比值在预测脓毒性休克患者90d死亡率中的作用。方法:收集在EICU入院的成人脓毒性休克患者共136例,按随访90d是否存活分为存活组与死亡组,记录两组患者基线特征、CRP、ALB数值,并计算CRP/ALB比值。采用统计学分析,确定各生物标记物对出院患者90d死亡率的诊断价值。结果:CRP dis及CRP/ALB dis较其他数据的AUC高,特异度亦较高,对出院后90d死亡有相对较好的诊断价值,二者比较差异有统计学意义,P=0.043。结论:CRP/ALB dis可作为脓毒性休克患者的长期预后指标。Objective.. Evaluation of the role of CRP/ALB ratio in predicting 90 days mortality in patients with septic shock. Method： 136 cases of adult septic shock patients in EICU were collected. The patients were divided into survival group and death group, and were followed up for 90 days. Baseline characteristics,CRP, ALB, and the ratio of CRP/ALB of the two groups were recorded. The diagnostic value of biomarkers for 90 days mortality of discharged patients was analyzed statistically. Result：The AUC and specificity of CRP and CRP/ALB ratio at dis- charge were higher than other data. Both have good relatively diagnostic value for the mortality of 90 days after discharge. The parameters had statistically significant difference, P= 0. 043. Conclusion.. CRP/ALB ratio can be used as a long-term prognostic indicators in patients with septic shock.

关 键 词：C-反应蛋白 白蛋白 脓毒性休克 预后 

分 类 号：R631[医药卫生—外科学] Q512.1[医药卫生—临床医学]