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作 者:孙克陆[1] 梁爱霞[1] 徐敏[1] 王景武[1] 李彬彬[1]
机构地区:[1]解放军第一〇五医院心内一科,安徽省合肥230031
出 处:《中国基层医药》2015年第5期699-701,共3页Chinese Journal of Primary Medicine and Pharmacy
摘 要:目的:分析冠心病慢性心力衰竭患者室性心律失常的治疗及发生情况。方法选取100例冠心病慢性心力衰竭患者,观察患者心力衰竭治疗及室性心律失常发生情况。结果100例患者中,并发室性心律失常44例,未并发室性心律失常56例;室性心律失常组氨基末端前脑钠尿肽(NT-proBNP)(3110.00±522.00)pg/mL,明显高于无室性心律失常组的(2200.00±486.00)pg/mL(t=8.996,P<0.05);其LVEF (0.25±0.08),明显低于无室性心律失常组的(0.41±0.98)(t=11.625,P<0.05);左心室内径≥70 mm组室性期前收缩发生率(100.00%)明显高于左心室内径60~69 mm组、50~59 mm组、40~49 mm组的室性期前收缩发生率(60.87%)、(37.04%)、(15.38%)(χ2=5.853、12.532、27.375,均P<0.05);应用胺碘酮组β受体阻滞剂使用量(20.80±6.70)mg,明显低于未应用胺碘酮组的(44.20±12.90)mg(t=5.284,P<0.05)。结论冠心病慢性心力衰竭患者并发心律失常后NT-proBNP升高,应用胺碘酮可减少抗心衰药物的剂量。Objective To analyze the treatment and pathogenetic condition of chronic heart failure of coro -nary heart disease(CHD) and ventricular arrhythmia (VA).Methods 100 patients with chronic heart failure were collected to observe the treatment of chronic heart failure and pathogenetic condition of VA .Results 44 cases occured VA and 56 cases without VA in 100 patients.NT-proBNP(3 110.00 ±522.00)pg/mL of VA group was sig-nificantly higher than that (2 200.00 ±486.00)pg/mL of non-VA group(t=8.996,P〈0.05).LVEF(0.25 ± 0.08) of VA group was lower than that of non -VA group(0.41 ±0.98) (t=11.625,P〈0.05).The occurrence (100.00%) of premature ventricular contraction ( PVC) of ≥70mm group in left ventricular internal diameter (LVID) was higher than that of 60 -69mm group (60.87%),50 -59mm group (37.04%),40 -49mm group (15.38%) with statistically significant(χ2 =5.853,12.532,27.375,all P〈0.05).The amount(44.20 ±12.90)mg of use βreceptor blockers of amiodarone group was significantly lower than that of non -amiodarone group(44.20 ± 12.90)mg (t=5.284,P〈0.05).Conclusion NT-proBNP of CHEF of CHD and VA patients will improve and amiodarone can reduce the amount of use anti -heart failure drug .
分 类 号:R541.4[医药卫生—心血管疾病] R541.7[医药卫生—内科学]
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