糖尿病患者唾液葡萄糖含量分析  

Analysis of the salivary glucose level in the patients with diabetes mellitus

作　　者：孙慧斌[1] 李宁毅[1] 钟德钰[1] 王颜刚[1] 初开秋[1] 

机构地区：[1]山东青岛大学医学院附属医院,266000

出　　处：《实用口腔医学杂志》2002年第4期344-346,共3页Journal of Practical Stomatology

摘　　要：目的 :研究糖尿病患者唾液中葡萄糖含量的改变 ,并观察高血糖状态下唾液糖与血糖的关系。方法 :实验组为 6 0例糖尿病患者 ,对照组为 6 0例正常人。收集实验组及对照组清晨非刺激状态下自然分泌的全唾液 ,进行葡萄糖含量分析 ,同时行空腹血糖分析。结果 :糖尿病组的唾液葡萄糖含量为 ( 1.95 0±0 .179)mmol/L ,高于对照组的 ( 0 .95 3± 0 .12 4)mmol/L ,二者有显著性差异 (P <0 .0 1)。糖尿病组的唾液葡萄糖含量与血糖浓度有显著直线相关性 (P <0 .0 5 )。结论 :糖尿病患者唾液腺分泌功能发生改变 ,这可能是机体在长期高血糖状态下对唾液腺的损害 。Objective: To analyse the level of glucose concentration in saliva and to study the relationship between the level of blood glucose and that of salivary glucose.Methods: Blood glucose level and the glucose concentration in unstimulated mixed saliva taken from testee were measured with Beckman SYNCHRON CX7 System in 60 patients with diabetes mellitus and 60 healthy subjects. Results: The average value of salivary glucose concentration in experimental group was (1.950±0.179) mmol/L, that in control group was (0.953±0.124) mmol/L(P<0.01).Linear regression of salivary glucose was correlated significantly with blood glucose with a correlation coefficient of 0.210(P<0.05). Conclusion: The salivary glucose concentration in patients with diabetes mellitus is higher than that in healthy subjects. It indicates that the secretion function of salivary gland may be destroyed under the status of high blood glucose.

关 键 词：糖尿病 唾液 葡萄糖含量 口腔表现 血糖浓度 

分 类 号：R587.1[医药卫生—内分泌]