儿童过敏性疾病特应性进程研究进展  

Research progress on the atopic march of paediatric allergic diseases

作　　者：高琦[1] 向莉[1] 申昆玲[1] 

机构地区：[1]首都医科大学附属北京儿童医院过敏反应科,100045

出　　处：《国际儿科学杂志》2015年第2期189-192,共4页International Journal of Pediatrics

基　　金：国家自然科学基金（81100022）;北京市卫生系统高层次卫生技术人才培养计划（2011-3-053）

摘　　要：儿童过敏性疾病患病率日益增高,不容忽视.儿童过敏性疾病存在特应性进程的假说早在1985年即得到证实,具体是指婴儿或儿童早期出现的某种过敏反应症状常预示未来其他过敏性疾病的发生,众多纵向流行病学研究支持这一假说,其中以来自欧洲和北美的研究居多,亦有研究对此假说提出质疑.儿童过敏进程受诸多因素影响,如早年喘息、性别、父母过敏史等.该文就相关研究展开综述,以对高危患儿的识别和及时干预提供线索.Prevalence rates of paediatric allergic diseases have been gradually increasing worldwide,which cannot be ignored.The theory of atopic march of paediatric allergic diseases has been verified as early in 1985.The atopic march refers to that allergic symptoms in infancy or early childhood often predate development of other allergic diseases later in life.A number of longitudinal epidemiological studies support this theory,mainly from Europe and North America.However,there are some challenges to this theory.Allergic disease in children is influenced by various factors such as early wheezing,gender and a parental history of allergic diseases.This article reviews the latest progress on the atopic march of paediatric allergic diseases,which may provide clues to the early recognition and management of children at high risk of these diseases.

关 键 词：儿童 特应性皮炎 过敏性鼻炎 哮喘 

分 类 号：R725.9[医药卫生—儿科]