二尖瓣置换术后凝血功能测定的临床价值  

Clinical value of determination of blood coagulation function after mitral valve replacement

作　　者：马建新[1] 徐忠玉[1] 谢志雄[1] 朱小东[1] 叶金宝[1] 

机构地区：[1]解放军第175医院/厦门大学附属东南医院检验科,福建漳州363000

出　　处：《国际检验医学杂志》2015年第6期774-775,777,共3页International Journal of Laboratory Medicine

摘　　要：目的探讨二尖瓣置换术(MVR)后患者凝血功能的变化及临床价值。方法将2012年1月至2014年1月期间收治入该院进行MVR后患者163例纳入观察组,将同期来该院同期健康体检者163例纳入对照组,检测两组患者的凝血酶原时间(PT)、部分活化凝血酶原时间(APTT)、纤维蛋白原(FIB)浓度、凝血酶时间(TT)和凝血酶原时间国际标准化指数(INR),并进行统计学分析。结果观察组大多数PT、APTT、INR均明显高于对照组,差异有统计学意义(P<0.05)。结论 MVR后患者定期测定凝血功能可以有效反映患者体内抗凝及凝血机制紊乱的现状,可提高诊断及治疗的效率和临床预测价值。Objective To investigate the changes and clinical significance of the coagulation function after mitral valve replace‐ment （MVR） .Methods 163 cases of MVR admitted in our hospital from January 2012 to January 2014 were included in the obser‐vation group and contemporaneous 163 individuals of healthy physical examination were selected as the control group .The pro‐thrombin time （PT） ,activated partial thromboplastin time （APTT ） ,fibrinogen concentration （FIB） ,thrombin time （TT ） and pro‐thrombin time international normalized ratio （INR） in the two groups were detected and the detected results were performed the statistically comparative analysis .Results PT ,APTT and INR in the majority of the observation group were significantly higher than those in the control group ,the differences had statistical significance （P 〈 0 .05） .Conclusion The regular determination of blood coagulation function after MVR can effectively reflect the disorder status of anticoagulant and coagulation mechanism ,and can improve the efficiency of diagnosis and treatment and clinical predictive value .

关 键 词：二尖瓣置换术 凝血指标 临床预测价值 

分 类 号：R654.2[医药卫生—外科学] R446.11[医药卫生—临床医学]