二维超声斑点追踪及组织多普勒技术评价系统性红斑狼疮患者心室纵向收缩功能  

Evaluation on cardiac longitudinal systolic function in patients with systemic lupus erythematosus using two-dimensional speckle tracking imaging and tissue Doppler imaging

作　　者：张贺彬[1] 郑哲岚[1] 林胜文[2] 应鸣[2] 陈丽[2] 

机构地区：[1]浙江大学医学院附属第一医院心血管超声中心,浙江杭州310003 [2]浙江中医药大学附属第二医院超声科,浙江杭州310005

出　　处：《中国医学影像技术》2015年第3期385-388,共4页Chinese Journal of Medical Imaging Technology

摘　　要：目的评价系统性红斑狼疮(SLE)患者左、右心室纵向收缩功能。方法对49例SLE患者(SLE组)与33名健康对照者(对照组)均行超声心动图检查,并应用二维斑点追踪及组织多普勒技术获取三尖瓣瓣环位移(TAPSE)、三尖瓣瓣环等容收缩期速度(IVCv)和三尖瓣瓣环收缩期速度(PSv)。应用QLab 9.0软件分析获得左心室整体纵向应变值(GLS)。结果 SLE组GLS值、TAPSE、IVCv及PSv均低于对照组,差异均有统计学意义(P均<0.01)。SLE组中抗心肌抗体(AMA)阴性者TAPSE和PSv低于对照组(P均<0.05)。GLS与左心室射血分数(LVEF)、TAPSE、IVCv及PSv有一定的相关性(r=-0.57、-0.76、-0.81、-0.78,P均<0.01)。结论 SLE患者左、右心室纵向收缩功能有不同程度的受损。Objective To explore the cardiac longitudinal systolic function in patients with systemic lupus erythematosus（SLE）.Methods Forty-nine patients with SLE（SLE group）and thirty-three healthy controls（control group）were collected and underwent transthoracic echocardiography,as well as two-dimensional speckle tracking imaging and tissue Doppler imaging,and then the tricuspid annular plane systolic excursion（TAPSE）,isovolumic contraction peak velocity at the tricuspid annulus（IVCv）,peak systolic velocity（PSv）were measured.Global longitudinal strain（GLS）was calculated via QLab 9.0analysis software offline.Results Compared with control group,the GLS,TAPSE,IVCv and PSv reduced in SLE group（all P〈0.01）.The TAPSE and PSv in patients with negative antimyocardial antibody（AMA）were lower than those in control group（all P〈0.05）.The left ventricular ejection fraction（LVEF）,TAPSE,IVCv and PSv were correlated with GLS（r=-0.57,-0.76,-0.81,-0.78,all P〈0.01）.Conclusion The longitudinal systolic function of left and right ventricle are impaired in patients with SLE.

关 键 词：超声心动描记术 系统性红斑狼疮 心室功能 应变 斑点追踪成像 组织多普勒成像 

分 类 号：R540.45[医药卫生—心血管疾病] R593.241[医药卫生—内科学]