浙江省宁波市居民甲状腺结节的危险因素分析  

Risk factors for thyroid nodules among residents of Ningbo City in Zhejiang Province

作　　者：赵薛飞[1] 张劼楠[1] 孙亚维[1] 姚漫红[1] 朱国良[1] 董红军[1] 

机构地区：[1]浙江省宁波市疾病预防控制中心寄生虫与地方病防治所,315010

出　　处：《中华地方病学杂志》2015年第3期213-216,共4页Chinese Journal of Endemiology

摘　　要：目的 了解宁波市居民甲状腺结节患病状况,探讨甲状腺结节的相关危险因素.方法 2011年,在宁波市采用多阶段分层整群随机抽样方法抽取6 ～ 70岁居民3 596人,对调查人群进行盐碘、尿碘检测及甲状腺B超检查.采用单因素及多因素Logistic回归进行相关的危险因素分析.结果 宁波市居民甲状腺结节检出率为22.66％（815/3 596）,标准化检出率为17.69％.女性[vs.男性,比值比（OR）=2.06,95％可信区间（a）为1.74 ～ 2.43]、年龄[vs.6岁～组,18岁～（OR=3.42,95％CI=1.22 ～ 9.61）、40岁～（OR=13.06,95％CI=4.80～ 35.51）、65岁～（OR=16.67,95％CI=5.97～46.54）]和食用海鲜食品＜2次/周（vs.≥2次/周,OR=1.23,95％CI=1.02～ 1.49）是甲状腺结节的影响因素.结论 未发现人群碘营养与甲状腺结节的发生存在关联,女性、年龄≥18岁人群是甲状腺结节发生的危险因素,经常食用海鲜食品可能降低甲状腺结节的发生.Objective To investigate the prevalence of thyroid nodules among residents of Ningbo City and to explore the risk factors for thyroid nodules.Methods Totally 3 596 residents aged 6-70 were selected by multistage stratified cluster random sampling in Ningbo City,2011.Thyroid ultrasound examination was performed in all participants,while salt iodine and urinary iodine were measured.Possible risk factors for thyroid nodules were analyzed by single factor and multi-factor logistic regression.Results The prevalence rate of thyroid nodules in residents of Ningbo City was 22.66％ （815/3 596）,with standardized prevalence rate of 17.69％.Female [（odds ratio （OR） =2.06,95％ confidence interval （CI） =1.74-2.43],groups of aged 18-（OR =3.42,95％ CI =1.22-9.61）,aged 40-（OR =13.06,95％ CI =4.80-35.51）,aged 65-（OR =16.67,95％ CI =5.97-46.54） and occasional consumption of seafood habits （less than twice per week,OR =1.23,95％ CI =1.02-1.49） were significant associated with thyroid nodules.Conclusions There is no link Letween iodine nutrition and thyroid nodules.It is demonstrated that female and aged ≥ 18 groups have higher risk of thyroid nodules; frequent consumption of seafood seems to be a protective factor.

关 键 词：甲状腺结节 碘 危险因素 分析 

分 类 号：R581[医药卫生—内分泌]