眼睛动态检测系统在神经疾病定位诊断中的初步应用  

Initial Application of Eyes Dynamic Detection System in the Nerve Localization Diagnosis

作　　者：颜红金[1] 高庆春[2] 李现亮[2] 张永林[3] 

机构地区：[1]广州医科大学生物医学工程系,广东广州510182 [2]广州医科大学附属第二医院神经内科,广东广州510260 [3]暨南大学光电工程研究所,广东广州510632

出　　处：《中国医学物理学杂志》2015年第2期251-254,共4页Chinese Journal of Medical Physics

基　　金：广州医科大学博士启动项目(L110514)

摘　　要：目的:探讨光反射传导径路出现异常引起眼睛变化的特点,研究眼睛的动态检测对光反射传导径路出现异常的神经性病变定位诊断的价值。方法:观察分析病例,在暗视条件下,应用本课题组设计的眼睛动态检测系统检测病例的瞳孔及其对光反射。瞳孔对光反射检查是在左右两侧分别给予光刺激时,定量检测双侧眼的瞳孔变化情况。检测的特征值包括瞳孔初始直径(D0)、瞳孔收缩速度(V)等。根据其眼睛的动态变化情况,作出传导径路出现神经病变的定位分析。结果:病例的瞳孔大小和瞳孔对光反射都出现了异常现象,但各自有不同的特点。病例C的左侧瞳孔明显小于右侧,左眼的直接对光反射消失、间接对光反射也消失;右眼直接对光反射存在、间接对光反射也存在。病例D的右侧瞳孔明显小于左侧,右眼直接对光反射消失,间接对光反射虽然幅度小,但存在;左眼直接对光反射存在,间接对光反射消失。结论:眼睛动态检测可起到对光反射传导径路异常的神经疾病定位分析和鉴别诊断的重要作用。Objective We explored the eyes change caused by abnormal conduction path of light reflecting. The value of eyes dynamic detection was explored in localization diagnosis when light-reflecting pathways was abnormal. Methods We observed and analyzed the cases of abnormal ocular symptoms. In dark conditions, pupillary light reflex was detected with the eyes dynamic detection system designed by our research group. Both eyes were observed when the left side and the right side were respectively given light stimulus, and changes in bilateral pupil were quantitatively detected. The characteristic value of detection includes the initial pupil diameter （Do）, the pupil contraction velocity （V） and so on. Results The left pupil of case C is significantly less than the right one. The direct and indirect light reflex of the left eye was disappeared, but there is a direct and indirect light reflex in the right eye. The right pupil of case D is significantly less than the left one. The direct light reflex of the right eye was disappeared. The indirect light reflex of the right eye exited, though the indirect light reflex amplitude is small. The direct light reflex of the left eye exited. The indirect light reflex of the left eye was disappeared. Conclusion Eyes dynamic detection can play important role in the positioning analysis and differential diagnosis, when the light reflex conduction pathway is abnormal.

关 键 词：眼睛 动态检测 光反射 神经疾病 定位诊断 

分 类 号：R318.6[医药卫生—生物医学工程]