多田公式计算脑内血肿体积的准确性和可靠性  

Study on the Accuracy and Reliability of the ABC/2 Formula for Volume Assessment of Intracerebral Hematoma

作　　者：徐兴华[1] 陈晓雷[1] 张军[1] 许百男[1] 

机构地区：[1]中国人民解放军总医院神经外科,北京100853

出　　处：《中国神经精神疾病杂志》2015年第2期87-91,共5页Chinese Journal of Nervous and Mental Diseases

基　　金：国家自然科学基金项目(编号:81271515)

摘　　要：目的通过与3D-Slicer软件测量结果比较,研究多田公式计算脑出血后血肿体积的准确性和可靠性。方法收集184例自发性脑出血患者的头颅CT数据资料,分别采用多田公式和3D-Slicer软件测量血肿体积。将血肿按3D-Slicer测得体积分为：一组〈30mL（n=55）,二组30-60mL（n=68）,三组〉60mL（n=61）;按形状分组：规则组（n=59）,不规则组（n=107）和分叶状组（n=18）。分别根据血肿大小和形状对两种方法测量结果进行分析比较。结果多田公式法血肿平均体积（58.85±37.38）mL,3D-Slicer软件法血肿平均体积（50.08±31.10）mL,差异有统计学意义（t=8.254,P〈0.01）,多田公式平均测量误差8.77mL,误差率17.23%。按血肿大小分组,多田公式法测量误差：一组2.90mL（16.22%）,二组5.89mL（13.55%）,三组17.27mL（18.76%）;按血肿形状分组,多田公式测量误差：规则组3.46mL（8.76%）,不规则组7.99mL（17.26%）,分叶状组30.81mL（38.26%）。结论多田公式是一种粗略的血肿体积计算方法,结果存在较明显误差,误差大小主要取决于血肿形状。Objective To investigate the accuracy and reliability of the ABC/2 formula for measurement of intracerebral hematoma（ICH） volume by comparing it with software 3D-Slicer.MethodsComputed tomographic image data of184 patients with spontaneous ICH were collected. Hematoma volumes were estimated by using the ABC/2 formula and3D-Slicer. Based on the volume calculated by 3D-Slicer, patients were further divided into three groups. Group 1 contained 55 patients with volume less than 30 ml, group 2 contained 68 patients with volume of 30-60 ml, and group 3 contained 61 patients with volume larger than 60 mL. Shape of the ICH was divided into regular（59 cases）, irregular with frayed margins（107 cases） and multilobular（18 cases）.Resultsof these two methods were compared according to hematoma size and shape. Results The estimated hematoma volume was（58.85±37.38） mL in the ABC/2 formula and（50.08±31.10） mL in 3D Slicer. The ABC/2 formula produced a mean overestimation of 8.77 mL and the mean percent deviation was 17.23%. The mean estimation errors were 2.90 mL（16.22%）, 5.89 mL（13.55%）, and 17.27 mL（18.76%） in groups1, 2, and 3 when patients were grouped by hematoma size. The estimation errors were 3.46 mL（8.76%）, 7.99 mL（17.26%）, and 30.81 mL（38.26%） in regular, irregular and multilobular hematomas when patients were grouped by shape.ConclusionsThe ABC/2 formula is a rough method for volume assessment of intracerebral hematoma and produces significant estimation errors. The size of estimation errors largely depends on hematoma shape.

关 键 词：脑内血肿 血肿体积 多田公式 3D-Slicer 

分 类 号：R651.1[医药卫生—外科学]