双腔起搏器心室自身优先功能对病态窦房结综合征患者左心功能的影响  

The effect of VIP function in dual-chamber pacemaker system on left ventricular function of patients with sick sinus syndrome

作　　者：赵韧[1] 陈刚[1] 史学功[1] 李小虎[2] 林先和[1] 徐岩[1] 陈旭华[1] 周碧蓉[1] 陈斌[1] 李中清[1] 吕冶芳[1] 程自平[1] 

机构地区：[1]安徽医科大学第一附属医院心血管内科,合肥230022 [2]安徽医科大学第一附属医院放射科,合肥230022

出　　处：《安徽医科大学学报》2015年第3期383-385,共3页Acta Universitatis Medicinalis Anhui

基　　金：国家自然科学基金(编号:81301224);安徽省高校省级自然科学研究重点项目(编号:KJ2014A122;KJ2013A144);安徽医科大学第一附属医院青年科学基金培养计划项目(编号:2012KJ18;2012KJ02)

摘　　要：选择因病态窦房结综合征安装DDD心脏起搏器的患者31例。根据植入后是否开启心室自身优先(VIP)功能分为对照组(n=15)与观察组(n=16),随访起搏器参数,并观察累计心室起搏比例(Cum%VP)、左房内径(LAD)、左室舒张末期内径(LVEDD)、左室射血分数(LVEF)及6 min步行试验距离的变化。起搏器植入术后12个月,观察组与对照组比较Cum%VP比例明显降低(P<0.01);LVEDD显著减少(P<0.01);6 min步行试验距离显著增加(P<0.05)。DDD心脏起搏器VIP功能可以显著减少累计心室起搏比例,从而更好的保护左心功能。31 patients with sick sinus syndrome undergone dual-chamber pacemaker implantation were randomly divided into control group（n=15） and observation group（n=16） which was based on whether to run VIP func-tion. All the patients were followed-up by evaluating cumulative proportion of ventricular pacing （ Cum%VP） , left atria diameter （ LAD） , left ventricular end-diastolic diameter （ LVEDD） , left ventricular ejection fraction （ LVEF） and the distance of 6 min walk test after 12 months. All of the above parameters between the two groups were com-pared. After 12 months, the VIP function caused significant increase of the Cum% VP（P 〈0. 01）and LVEDD （P 〈0. 01） compared with the control group. The distance of 6min walk test was increased（P 〈0. 05） compared with the control group when VIP function was running. The VIP function of dual-chamber pacemaker could significantly reduce the proportion of cumulative ventricular pacing, in order to protect the left ventricular function.

关 键 词：心脏起搏 心室自身优先 左心功能 起搏器植入术 

分 类 号：R541.74[医药卫生—心血管疾病]