多发棕色瘤X线、CT及MRI表现  

Radiography,CT and MR Findings of Multiple Brown Tumors Caused by Primary Hyperparathyroidism

作　　者：白荣杰[1] 钱占华[1] 叶薇[1] 詹惠荔 刘悦[2] 李新民[1] 程晓光[1] 屈辉[1] 

机构地区：[1]北京积水潭医院放射科,100035 [2]哈尔滨医科大学附属第三临床医院,150081

出　　处：《临床放射学杂志》2015年第3期420-423,共4页Journal of Clinical Radiology

基　　金：国家自然科学基金面上项目(编号:81071130);北京市自然科学基金面上项目(编号:7102082);北京市卫生局"十百千"百层次人才培养资助项目

摘　　要：目的分析多发性棕色瘤的X线、CT和MRI表现,探讨其临床特点和鉴别诊断。方法 32例由原发性甲状旁腺机能亢进(PHPT)引起多发性棕色瘤患者,均经手术及病理证实,所有病例均行局部骨X线、CT和MRI检查,对其影像学表现进行对照分析。结果 32例PHPT患者均在全身不同部位出现棕色瘤病变,其中股骨病变15例、胫骨干15例、腓骨干12例、髂骨16例、椎体3例、肱骨3例、肋骨5例和指骨12例。结论 X线、CT和MRI从不同方面反映了多发性棕色瘤的病理改变,三种检查方法结合可更全面显示多发性棕色瘤的影像学特点,有利于定性和鉴别诊断。Objective To analyze radiography,CT and MRI manifestations of multiple brown tumors caused by primary hyperparathyroidism（ PHPT）,and to discuss its clinical features and differential diagnosis.Methods A total of 32 patients with pathologically-proved multiple brown tumors caused by primary hyperparathyroidism were included in this study.Radiography,CT and MRI were performed for the involved bones in all patients.The imaging findings were analyzed and compared with pathological results.Results In all the 32 patients with primary hyperparathyroidism,brown tumor lesions could be observed in different parts of body,including femur（ n = 15）,tibia（ n = 15）,fibula（ n = 12）,ilium（ n = 16）,vertebra（ n = 3）,humerus（ n = 3）,rib（ n = 5） and phalanx（ n = 12）.Conclusion Radiography,CT and MRI can reflect the pathological changes of multiple brown tumors from different aspects.Combination use of three imaging examination methods can comprehensively demonstrate the imaging characteristics,which is very helpful in making qualitative diagnosis and differential diagnosis.

关 键 词：多发性棕色瘤 原发性甲状旁腺机能亢进 X线摄影 CT磁共振成像 

分 类 号：R582.1[医药卫生—内分泌] R681[医药卫生—内科学] R816.8[医药卫生—临床医学]