SAPHO综合征的CT特征  

CT Characteristics of SAPHO Syndrome

作　　者：王广举[1] 张国安[1] 

机构地区：[1]辽宁抚顺矿务局总医院影像科,113008

出　　处：《临床放射学杂志》2015年第3期435-439,共5页Journal of Clinical Radiology

摘　　要：目的探讨SAPHO综合征的CT特征。方法回顾性分析42例SAPHO综合征患者CT表现及临床资料,所有病例行MSCT薄层扫描,6例行X线检查。结果 42例患者发病部位主要在胸骨、锁骨胸骨端、第一前肋及肋软骨、胸锁关节及胸肋关节,表现为骨质硬化肥厚,关节面破坏、关节间隙变窄,晚期以骨关节肥厚融合为主。对称性30例,非对称性12例,且均以右侧为重。皮肤受损40例,皮肤与骨关节同时发病11例,病程半年~30年不等。结论 SAPHO综合征具有固定发病部位及特征性影像学表现,MSCT扫描及其后处理技术是其最合理影像学检查方法。Objective To investigate the CT characteristics of synovitis,acne,pustolosis,hyperostosis and osteitis（ SAPHO） syndrome.Methods CT features and clinical data of 42 cases with SAPHO syndrome were retrospectively analyzed.Thin-slice MSCT scan was performed in all patients,and additional radiography was employed in 6 cases.Results The most common sites of the lesions were the sternum,sternal end of the clavicle,the first rib and costal cartilage,sterno-clavicular joint and sterno-costal joints.On CT scan,the lesions were characterized by bony sclerosis and hypertrophy,destruction of the articular surface and narrowing of joint space; and in late stage hypertrophy and fusion of the bone and joint were the main manifestations.The distribution of the lesions could be symmetric（ n = 30） or asymmetric（ n = 12）.Usually,the right side was more severe.Skin damage was seen in 40 cases,involvement of both skin and joint was observed in 11 cases.The course of the disease varied from 6 months to 30 years.Conclusion SAPHO syndrome has typical locations and characteristic imaging findings; MSCT scanning with post-processing technique is the most reliable imaging examination method.

关 键 词：SAPHO综合征 胸肋锁骨 掌跖脓疱疮 

分 类 号：R593.2[医药卫生—内科学] R816[医药卫生—临床医学]