头颈部嗜酸性淋巴肉芽肿的CT表现及临床病理分析  

CT features and clinicopathologic analysis of eosinophilic lymphogranuloma in head and neck region

作　　者：张力[1] 姚丽[2] 周玮玮[3] 于淑靖[1] 

机构地区：[1]沧州市中心医院CT诊断科,河北沧州061001 [2]沧州市中心医院VIP病房,河北沧州061001 [3]沧州市中心医院病理科,河北沧州061001

出　　处：《实用放射学杂志》2015年第3期376-378,383,共4页Journal of Practical Radiology

摘　　要：目的：探讨头颈部嗜酸性淋巴肉芽肿（ELG）的 CT 及临床、病理特征。方法回顾性分析经病理证实的9例头颈部ELG患者的CT及临床、病理资料。结果9例中单纯腮腺病变3例，单纯颈部淋巴结病变2例，两者同时受累4例。临床主要表现为头颈部无痛性结节或肿块，血嗜酸性粒细胞均明显增多。CT表现，腮腺结节病灶边界清晰或稍模糊，中等或明显均匀强化；腮腺弥漫性肿块病灶边界不清，可累及周围软组织，呈不均匀渐进性强化；颈部淋巴结表现为不同程度肿大，边界清晰，中等或明显均匀强化。病理学表现为大量嗜酸性粒细胞浸润、淋巴组织增生和滤泡形成、不同程度的纤维化、血管增生反应。结论头颈部 ELG的CT表现有一定特征，结合其临床表现及外周血嗜酸性粒细胞升高可提示诊断，确诊需要病理学检查。Objective To explore the CT,clinical,and pathological features of eosinophilic lymphogranuloma（ELG）in head and neck region. Methods CT,clinical,and pathological data of 9 cases of ELG in head and neck region,confirmed by biopsy were retrospectively an-alyzed.Results Parotid gland was lonely involved in 3 cases,and cervical lymph nodes were lonely involved in 2 cases,and they were both involved in 4 cases.All of the patients suffered from painless nodule or mass in head and neck region with peripheral blood eosinophilia.On CT examination,nodular lesions of parotid gland were clear or slightly blurred defined with moderately or obviously homogeneous enhancement,and diffuse mass lesions in parotid gland were ill defined with involvement of surrounding tissue,and heterogenous progressive enhancement.The involved cervical lymph nodes were enlarged with clear boundaries,and moderately or obviously homogeneous enhancement.The pathological findings of ELG included the marked infiltration of eosinophilia,lymphocytic proliferation,lymphatic follicles,variable degrees of fibrosis and vascular proliferation.Conclusion ELG in head and neck region has some CT features,and diagnosis could be suggested combining with the clinical manifestations and peripheral blood eosinophilia. The final diagnosis depends on histopathological examination.

关 键 词：嗜酸性淋巴肉芽肿 计算机体层成像 病理学 

分 类 号：R816.1[医药卫生—放射医学] R814.42[医药卫生—临床医学]