麦滋林颗粒联合间苯三酚注射液治疗孕妇急性胃炎疗效观察  

Clinical Effect of Marzulene-S Granules Combined with Phloroglucinol Injections in the Treatment of Pregnant Women with Acute Gastritis

作　　者：刘姗姗[1] 徐丘卡[1] 陈锐[1] 胡炜科[2] 

机构地区：[1]宁波市妇女儿童医院内科,浙江宁波315000 [2]宁波市第一医院急诊科

出　　处：《中国药师》2015年第4期602-603,615,共3页China Pharmacist

摘　　要：目的:观察麦滋林颗粒联合间苯三酚注射液治疗孕妇急性胃炎的临床疗效。方法:102例急性胃炎孕妇采用随机数字法分为两组各51例。对照组予麦滋林颗粒0.67 g,餐前30 min用温水冲服,tid,观察组在对照组基础上加用间苯三酚注射液80 mg+0.9%氯化钠注射液20 ml,ivd qd。疗程均为2周。观察两组临床疗效,比较两组治疗前后症状积分变化及症状缓解时间。结果:观察组有效率明显高于对照组(94.12%vs 78.43%,P<0.05),观察组治疗后胃脘痛、嗳气、口干积分较前明显下降(P<0.05),且明显低于对照组(P<0.05)。观察组和对照组腹痛消失时间分别为(1.8±0.4)d和(3.9±1.1)d,差异有统计学意义(P<0.05)。两组患者治疗中均未出现严重不良反应。结论:采用麦滋林颗粒联合间苯三酚注射液治疗孕妇急性胃炎临床效果较好。Objective： To observe the clinical effect of marzulene-S granules combined with phloroglucinol injections in the treatment of pregnant women with acute gastritis. Methods： Totally 102 cases of pregnant women with acute gastritis were randomly assigned into two groups with 51 cases in each. The control group was treated with marzulene-S granules 30 min before meals with warm water,0. 67 g,tid,and the observation group was additionally given phloroglucinol injection 80 mg in 0. 9% sodium chloride injections20 ml,ivd,qd. The treatment course was 2 weeks. The clinical curative effect of the two groups was observed before and after the treatment,and the symptom score changes and symptom remission time were compared as well. Results： The effective rate of the observation group was significantly higher than that of the control group（ 94. 12% vs 78. 43%,P〈0. 05）. After the treatment,the integral of epigastric pain,belching and dry mouth in the observation group was decreased significantly than that before the treatment（ P〈0. 05）,and significantly lower than that in the control group（ P〈0. 05）. The time of abdominal pain was（ 1. 8 ＋ 0. 4） d and（ 3. 9 ＋ 1. 1） d in the observation group and the control group,respectively,and the difference was statistically significant（ P〈0. 05）. No serious adverse reactions were found in the two groups. Conclusion： Marzulene-S granules combined with phloroglucinol injections in the treatment of pregnant women with acute gastritis is effective.

关 键 词：孕妇 急性胃炎 麦滋林颗粒 间苯三酚注射液 

分 类 号：R975[医药卫生—药品]