BMPR1B基因在寒泊肉羊世代选育中的遗传变异及其与产羔性状的关联分析  

Association of BMPR1B gene with litter size trait and genetic variations in different generations of Hanper mutton sheep

作　　者：陈晓勇[1] 孙洪新[1] 田树军[2] 敦伟涛[1] 

机构地区：[1]河北省畜牧兽医研究所,河北保定071001 [2]河北农业大学动物科技学院,河北保定071001

出　　处：《河北农业大学学报》2015年第2期99-102,共4页Journal of Hebei Agricultural University

基　　金：河北省属公益科研院所项目(11240413D);河北省科技支撑计划项目(14226315D)

摘　　要：为了探讨BMPR1B(A746G)基因在寒泊肉羊世代选育中的遗传变异及其与产羔数的关系,本试验分析了不同选育世代寒泊肉羊BMPR1B基因型和基因频率,基因型对不同世代母羊产羔数的影响。结果表明BMPR1B基因突变纯合型BB个体从第一世代就开始出现,BB基因型频率随选育世代增加呈现增加趋势,从G1到G2世代,BB基因型频率显著增加。G1世代B+基因型母羊产羔数高于++基因型,但差异不显著。G2世代BB基因型母羊产羔数达到3.0,显著大于B+(1.89)和++(1.24)基因型个体(P<0.01)。G1和G2世代BMPR1B基因型母羊对初产日龄和产羔间隔均无显著影响(P>0.05)。结果提示BMPR1B基因作为分子标记可显著提高寒泊肉羊新种群母羊产羔数。The aim of this study was to research the variation of BMPR1B （A746G） gene dur- ing generation selection and its association with litter size of Hanper mutton sheep. We ana- lyzed the genotypic and genic frequency of BMPR1B gene, and the effects of genotypes on lit- ter size of ewes during different selection generations. The results indicated that the individu- als of BB genotype homozygotes appeared in the first generation, and BB genotype and genic frequency increased with selected generations. The litter size of ewes with B＋genotype was greater than that of ewes with＋ ＋ genotype insignificantly in the first generation （G1） （P〉0.05） ,however, the litter size of BB ewe was 3.0, which was higher than those of B＋ （1.89） and ＋＋ （1.24） in the second generation （G2） remarkably （P〈0. 01）. There was no effect of BM- PR1B genotype on the first birthing age and birthing interval in G1 and G2 （P〉0.05）. The a-bore results demonstrated that BMPRIB gene increased the litter size of ewes from new flock Hanper mutton sheep as molecular marker.

关 键 词：寒泊肉羊 BMPR1B基因 产羔数 产羔间隔 初产日龄 基因型频率 基因频率 

分 类 号：S813.3[农业科学—畜牧学]