同种异体脱细胞真皮用于HA义眼台暴露修复观察  

Clinical observation of using homologous acellular dermal matrix as repairing material in the exposure of orbital hydroxyapatite implants

作　　者：王超庆 李燕飞[1] 程秀春[1] 李琦[1] 范晓聪[1] 李静[1] 

机构地区：[1]济南市明水眼科医院,山东250200

出　　处：《中国实用眼科杂志》2015年第3期294-296,共3页Chinese Journal of Practical Ophthalmology

摘　　要：目的了解同种异体脱细胞真皮应用于羟基磷灰石（HA）义眼台植入术后暴露的修复治疗的有效性和安全性。方法对2010～2013年在济南市明水眼科医院就诊的13例（13只眼）HA义眼台暴露患者术中探查，初步判断HA义眼台植入术式及暴露的原因，应用脱细胞真皮覆盖的方法进行处理。结果13例患者术后结膜血运良好，无明显水肿及渗出，无切口哆开、感染等并发症。连续观察10个月，未见暴露复发迹象。结论脱细胞真皮材料容易获得，组织相容性好，抗感染能力强，有一定的柔韧性，引起的免疫反应轻微，作为一种细胞外基质，可引导自身组织的胶原纤维长入，对创面要求低易于成活。对修复HA义眼台植入术后眼台暴露是一种较好的材料。Objective To understand the security and effectiveness of using homologous acellular dermal as repairing material in the exposure of orbital hydroxyapatite （HA） implants. Methods By 13 cases （13 eyes） hydroxyapatite implant exposure with intraoperative exploration, to initially judge implantation methods and exposure reasons of orbital implants, and using homologous acellular dermal as repairing material. Results Thirteen cases of postoperative conjunctival blood supply were good, no obvious edema and exudation, no incision dehiscence, infection and other complications. In continuous observation of 10 months, no evidence of exposure recurred. Conclusions Acellular dermal material is readily available, and has good tissue compatibility, resistance to infection, certain flexibility, and the immune response induced is light. Acellular dermal as a extracellular matrix can guide the organization＇s own collagen fibers ingrowth, and is easy to survive. For the repair of HA orbital implants after implant exposure is a good material.

关 键 词：同种异体脱细胞真皮 HA 义眼台 暴露 

分 类 号：R644[医药卫生—外科学]