抑木扶土方治疗腹泻型肠易激综合征肝气乘脾证临床观察  

Treatment of diarrhea-predominant irritable bowel syndrome of liver qi subjugating spleen pattern with “Yimu Futu Formula”

作　　者：辛红[1] 王小萍[1] 张正利[2] 李熠萌[2] 张金泉[1] 徐文蓉[1] 蔡淦[2] 

机构地区：[1]上海市黄浦区中西医结合医院脾胃病专科,上海200010 [2]上海中医药大学附属曙光医院消化科,上海200021

出　　处：《上海中医药杂志》2015年第4期47-49,共3页Shanghai Journal of Traditional Chinese Medicine

基　　金：上海市卫计委中医药事业发展三年行动计划-优秀青年中医临床人才培养计划项目(ZYSNXD011-RC-XLXX-20110014)

摘　　要：目的观察抑木扶土方治疗腹泻型肠易激综合征(IBS-D)肝气乘脾证的临床疗效。方法将60例肝气乘脾证IBS-D患者随机分为两组,每组30例;治疗组给予抑木扶土方治疗,对照组口服匹维溴胺片;两组疗程均为4周,观察临床疗效及IBS肠道症状评分和生活质量评分变化情况。结果治疗组总有效率为93.3%,对照组为73.3%;治疗组临床疗效优于对照组(P<0.05)。治疗后,两组肠道症状积分较治疗前显著降低(P<0.01),且治疗组腹痛程度等症状积分降幅大于对照组(P<0.05,P<0.01)。治疗后,两组生活质量积分均较治疗前显著增加(P<0.01),且治疗组生活质量积分增幅大于对照组(P<0.01)。结论抑木扶土方治疗肝气乘脾证IBS-D可改善临床症状和提高患者生活质量。Objective To observe the clinical efficacy of ＂Yimu Futu Formula＂for the treatment of diarrhea-predominant irritable bowel syndrome（ IBS-D） of liver qi subjugating spleen pattern. Methods Sixty cases with IBS-D were randomized into treatment group and control group,with 30 cases in each group. The treatment group was treated with＂Yimu Futu Formula＂,and control group was treated with pinaverium bromide,with the course of 4 weeks. The clinical efficacy,IBS symptom score and life quality score were observed. Results The total effective rate was 93. 3% in the treatment group and 73. 3% in the control group,with a difference between the two groups（ P 〈 0. 05）. After treatment,the IBS symptom score in both groups were decreased（ P 〈 0. 01）,and the reduction of symptom score in the treatment group was much more than that of the controls（ P 〈 0. 05,P 〈 0. 01）. After treatment,the life quality score in both groups were decreased（ P 〈 0. 01）,and increase of the treatment group was much more than that of the controls（ P 〈 0. 01）. Conclusion ＂Yimu Futu Formula＂is effective to improve the clinical symptoms in patients with IBS-D and improve their quality of life.

关 键 词：抑木扶土方 腹泻型肠易激综合征 肝气乘脾证 

分 类 号：R259[医药卫生—中西医结合]