不同人体质量指数下肺炎患儿临床特征的对比  

Comparison of clinical characteristics in children patients with pneumonia under different body mass indexes

作　　者：祁晓芳[1] 郭鲁闽[1] 姚开虎[2] 

机构地区：[1]中国人民武装警察部队山东省总队医院小儿内科,山东济南250014 [2]首都医科大学附属北京儿童医院小儿内科,北京100045

出　　处：《重庆医学》2015年第11期1475-1477,共3页Chongqing medicine

基　　金：国家自然科学基金资助项目(30801259)

摘　　要：目的探讨不同人体质量指数(BMI)下肺炎患儿临床特征的差异,为其临床研究提供可参考依据。方法选择中国人民武装警察部队山东省总队医院诊断为肺炎的患儿160例,根据其BMI分为BMI正常组(15.00<BMI<18.00kg/m2)、超重组(18.00≤BMI<20.00kg/m2)和肥胖组(BMI≥20.00kg/m2)。详细记录其临床表现及相关检查结果,对其临床特征进行比较。结果 160例肺炎患儿中正常体质量组33例(20.62%),超重组87例(54.38%),肥胖组40例(25.00%);BMI正常组住院时间明显低于肥胖组与超重组(P<0.05)。肥胖组高敏C-反应蛋白(hs-CRP)、白细胞介素-8(IL-8)均高于BMI正常组与超重组(P<0.05);超重组hs-CRP、IL-8均高于BMI正常组(P<0.05)。肥胖组IgG、IgA均低于BMI正常组与超重组(P<0.05),而CD4、CD4/CD8高于BMI正常组与超重组(P<0.05);超重组IgG、IgA均低于BMI正常组(P<0.05),CD4、CD4/CD8高于BMI正常组(P<0.05)。肥胖组一秒用力呼气容积(FEV1)、肺活量(VC)、FEV1/用力肺活量(FVC)均低于BMI正常组与超重组(P<0.05)。结论随着BMI的增加,肺炎患儿的住院时间延长、肺功能更容易受损,炎性反应及免疫异常在肥胖患儿肺炎的发生过程中起重要作用。Objective To study the differences of clinical characteristics in the children patients with pneumonia under differ‐ent body mass indexes（BMI） to provide the basis for its clinical research .Methods 160 children patients with pneumonia in the Shandong Armed Police Corps Hospital were selected and divided into the normal BMI group （15 .00〈BMI〈18 .00 kg/m2 ） ,the o‐verweight group （18 .00≤BMI〈20 .00 kg/m2 ） and the obese group （BMI≥20 .00 kg/m2 ） according to BMI .The clinical manifes‐tations and the relevant examination results were recorded in detail .Their clinical manifestations were compared among 3 groups . Results Among 160 cases of pneumonia ,33 cases （20 .62% ） were in the normal BMI group ,87 cases （54 .38% ） were in the over‐weight group and 40 cases（25 .00% ） were in the obese group .The hospital stay time in the normal BMI group was lower than that in the obese group and overweight group （P〈0 .05） .The hs‐CRP and IL‐8 levels in the obese group were higher than those in the normal BMI group and the overweight group （P〈 0 .05） .The hs‐CRP and IL‐8 levels in the overweight group were higher than those in the normal BMI group （P〈0 .05） .The IgG and IgA levels in the obese group were lower than those in the normal BMI group and the overweight group （P〈0 .05） .The IgG and IgA levels in the overweight group were lower than those in the normal BMI group （P〈0 .05） .The CD4 level and CD4/CD8 ratio in the obese group were higher than those in the normal weight group and the overweight group（P〈0 .05） .The CD4 level and CD4/CD8 ratio in the overweight group were higher than those in the nor‐mal BMI group （P〈0 .05） .The FEV1 ,VC ,FEV1/FVC in the obese group were lower than those in the normal weight group and the overweight group（P〈0 .05） .Conclusion Along with BMI increase ,the hospitalization time is extended and the lung function is easy to be injured .The inflammatory reaction and immune abnormality play an im

关 键 词：人体质量指数 肺炎 儿童 患者 临床特征 

分 类 号：R725.6[医药卫生—儿科]