低剂量与常规剂量螺旋CT显示磨玻璃密度结节的对照研究  

Comparative study of low-dose and standard-dose spiral CT in the detection of ground-glass nodule

作　　者：魏然[1,2] 李万湖[1] 申洪明[1] 崔永春[1] 

机构地区：[1]山东省医学科学院山东省肿瘤研究防治院放射科,山东济南250117 [2]济南大学山东省医学科学院医学与生命科学学院,山东济南250001

出　　处：《医学影像学杂志》2015年第3期452-454,共3页Journal of Medical Imaging

摘　　要：目的探讨低剂量及常规剂量螺旋CT扫描在检出磨玻璃密度肺结节（ground-glass nodule,GGN）的数目、边缘、内部结构与周边结构是否在统计学上存在显著差异。方法对经常规剂量（200mA）与层厚（5mm）螺旋CT扫描发现GGN患者56例同时行肺部低剂量（30mA）螺旋CT扫描,所得图像分别重建2mm、1mm,并按结节直径〈5mm,5～10mm,〉10mm不同大小分组,记录结节数目、边缘、内部特征以及周边结构等。结果低剂量与常规剂量螺旋CT扫描在检出GGN的数目、边缘、内部结构与周边结构无统计学意义。结论30mA低剂量螺旋CT扫描及层厚2mm可对GGN作出较好的判断,值得在早期肺癌筛查中应用。Objective To discuss the performance of the low-dose and standard dose scanning protocol in detecting the number and margin and central and peripheral structure of Ground-Glass Nodule（GGN）at spiral CT.Methods As GGN were detected in 56 patients at the standard dose spiral CT（200mA,collimation 5mm）,we repeated low-dose spiral CT（30mA）.Images of 2mm and 1mm were reconstructed respectively.According to the size,the nodules were categorized as〈5mm,5～10mm and 〉10 mm nodules.The number and margin and central and peripheral structure of the nodule were recorded and compared between the standard dose and low-dose scanning protocol groups.Results There was no significant difference in the number,margin,central and peripheral structure of the GGN detected by the standard dose from the low-dose spiral CT scanning.Conclusion The 30 mA low-dose spiral CT scanning and collimation 2mm could provide adequate images to detect or exclude GGN,thus,it might be used reliably in the early lung cancer screening.

关 键 词：低剂量 磨玻璃密度肺结节 层厚 体层摄影术 X线计算机 

分 类 号：R814.42[医药卫生—影像医学与核医学] R734.2[医药卫生—放射医学]