糖尿病患者感染的病原菌分布与耐药性研究  

Distribution of infected diabetic patients and drug resistance of pathogenic bacteria

作　　者：刘敏洁[1] 李高申[2] 薛现军[1] 郑勇[3] 

机构地区：[1]濮阳市油田总医院内分泌科,河南濮阳457001 [2]黄河科技学院医学院,河南郑州450000 [3]濮阳市油田总医院心胸外科,河南濮阳457001

出　　处：《中华医院感染学杂志》2015年第7期1507-1508,1529,共3页Chinese Journal of Nosocomiology

基　　金：国家自然科学基金资助项目(81172573)

摘　　要：目的探讨糖尿病患者感染的病原菌分布、耐药性及影响感染的相关因素,并提出针对性对策,以降低感染率。方法选取2012年12月-2013年12月180例糖尿病患者,对感染患者送检标本进行培养,采用ATB微生物鉴定仪进行细菌检测,使用K-B法进行药敏试验,数据采用SPSS 16.0进行统计分析。结果 180例患者中71例发生感染,感染率39.44%;共分离出105株病原菌,以金黄色葡萄球菌为主,共30株占28.57%;抗菌药物不合理使用、神经缺血性伤口、合并基础性疾病、住院1年>2次与患者发生感染密切相关(P<0.05)。结论糖尿病患者感染发生率较高,通过基础护理、血糖控制、感染控制等对策,能有效降低感染发生率。OBJECTIVE To investigate the distribution of pathogens for infections in diabetic patients,drug resistance and related factors affecting infections,and propose specific measures to reduce infection rates.METHODS Totally 180 cases of diabetes during Dec.2012 to Dec.2013 were selected.The samples from patients were cultured and analyzed for pathogen detection by ATB microbe system（France）and drug susceptibility test by K-B method.The software SPSS 16.0was used for statistical analysis of data.RESULTS Totally 71 out of 180 patients had infections with the infection rate of 39.44%.Totally 105 pathogens were isolated,the most prevalent ones were Staphylococcus aureus（30strains,28.57%）.Irrational use of antimicrobial drugs,neurological ischemic wounds,underlying diseases,the number of hospitalization times more than twice a year had a close relationship with infections in patients（P〈0.05）.CONCLUSIONThe incidence of infections in diabetic patients was high and countermeasures such as primary care,glycolic control,and infection control can effectively reduce the incidence of infection.

关 键 词：糖尿病 临床感染 病原菌 耐药性 危险因素 

分 类 号：R378[医药卫生—病原生物学]