支撑颈镜的研制及应用  

Endoscopic thyroidectomy with novel retractor in rabbits

作　　者：黄晨[1] 刘丽然[2] 欧阳电[2] 

机构地区：[1]广东省信宜市人民医院耳鼻咽喉-头颈外科,525300 [2]中山大学肿瘤防治中心华南肿瘤学国家重点实验室头颈科,广州510060

出　　处：《广东医学》2015年第5期678-680,共3页Guangdong Medical Journal

摘　　要：目的评定专利产品——支撑颈镜的安全性。方法 30只新西兰兔随机分为内镜组和开放组,每组15只。开放组常规方法切除左侧甲状腺,内镜组运用自主研制的支撑颈镜切除左侧甲状腺。术前1 d和术后1、3、5、7 d经耳缘静脉抽血,比较两组清中白细胞介素(IL)-6和C反应蛋白(CRP)的变化情况。结果内镜组手术均顺利完成,无并发症,亦无因调支撑颈镜使用伤及实验兔或产生其他不良影响。开放组和内镜组术后IL-6和CRP比较差异无统计学意义(P>0.05)。结论支撑喉镜的各项机械性指标如机械牵拉能力、悬吊角度、工作长度均到达手术要求。Objective To introduce and verify a novel surgical instruments which has been patented by the State Intellectual Property Office of the PRC.Methods Thirty female New Zealand white rabbits were divided into two experi -mental groups.The interleukin -6 （IL -6） and C -reactive protein （CRP） levels were measured preoperatively and on the 1st , 3rd and 7th day after operation.Statistical comparison between the 2 groups was performed using analysis of paired t test.Results This instrument enabled effortless change in positions and facilitated manipulation of the thyroid gland while protecting the adjacent carotid artery in operation .There was no statistically significant difference in IL -6 or CRP between the conventional thyroidectomy group and endoscopic thyroidectomy group .Conclusion The new instrument provides feasi-bility and safety of the endoscopic thyroidectomy in animal experiments .

关 键 词：动物实验 外科牵开器 外科手术 

分 类 号：R62[医药卫生—整形外科]