构筑手性金属有机骨架的方法及其在不对称催化中的应用  

Method of creating chiral metal-organic frameworks and its use in asymmetric catalysis

作　　者：刘丽丽[1] 台夕市[1] 刘美芳[1] 郭焕美[1] 晁明珠 

机构地区：[1]潍坊学院化学化工与环境工程学院,山东潍坊261061

出　　处：《化工进展》2015年第4期997-1006,共10页Chemical Industry and Engineering Progress

基　　金：国家自然科学基金(21171132);山东省优秀中青年科学家科研奖励基金(2014BSB01061);潍坊市科学技术发展计划(201301035)项目

摘　　要：手性金属有机骨架(MOF)具有独特的结构、不对称催化和手性拆分等性能,引起了催化学者的极大重视。系统地介绍了国内外有关手性MOF的合成方法,即:1非手性物质在晶体生长过程中自组装;2使用手性化合物来诱导合成;3通过手性有机基团与金属离子配位将手性成分嵌入金属有机骨架;4表面修饰的方法,第3种方法是最常用的合成手性MOF的方法。重点阐述了近年来手性MOF在不对称催化领域的最新研究成果,希望能为手性MOF研究者设计、合成更优良的手性MOF催化剂提供参考。未来手性MOF催化的主要目标在于合成性能更加高效、稳定的新型手性MOF催化剂,并应用于大规模工业生产中,在温和条件下实现较高的转化数和对映体选择性。Chiral metal-organic frameworks （MOFs） have attracted growing interest for their potential use in asymmetric catalysis and chiral separation,and on a more basic level,have called for the creation of new topologies in inorganic materials over the past few years. The synthesis methods of chiral MOF are discussed,includingⅠself-assembly based on achiral organic ligands;Ⅱ synthesis by chiral template;Ⅲ synthesis by chiral ligands;Ⅳ post-synthesis modification. “Synthesis by chiral ligands” is widely used in creating chiral MOFs. Accordingly,some applications of various chiral MOFs as catalysts are elaborated,hoping to offer some help to the designer of chiral MOFs. Usually as an asymmetric catalyst,chiral MOFs are capable of being very active for many reactions, such as epoxidation and Aldol reaction. The future main objective of chiral MOFs catalysis is to synthesize more excellent chiral MOF catalysts and be used in large-scale industrial production, achieving higher enantioselectivity and larger turn-over number under mild conditions.

关 键 词：配合物 合成 催化剂 化学反应 

分 类 号：O643.3[理学—物理化学] O627[理学—化学]