醒脑静联合果糖、纳洛酮治疗急性重度酒精中毒的疗效分析  

A Randomi zed Controlled Study of Xingnaojing Combined with Fructose, Naloxone in the Treatment of Acute Severe Alcoholism

作　　者：朱海荣[1] 谢扬[1] 李炯[1] 肖李锋[1] 林跃丰 

机构地区：[1]汕头大学医学院第二附属医院急诊科,广东汕头515041

出　　处：《现代诊断与治疗》2015年第3期483-485,共3页Modern Diagnosis and Treatment

摘　　要：目的观察醒脑静联合果糖、纳洛酮在治疗急性重度酒精中毒中的效果。方法选择我院2013年9月～2014年9月123例急性重度酒精中毒患者,根据收治顺位分为两组：单数61例患者为对照组,给予纳洛酮＋生理盐水联合治疗,双数62例患者在对照组基础上加用醒脑静注射液,并将纳洛酮组的溶剂生理盐水改为果糖注射液,观察两组救治效果。结果观察组共济失调期患者恢复清醒时间和症状消失时间分别为（74.8±20.4）min、（264.5±50.6）min,昏睡期患者恢复清醒时间和症状消失时间分别为（153.4±36.7）min、（420.7±102.8）min,均短于对照组,急救总有效率为98.38%,两组比较（P〈0.05）,差异有统计学意义。结论醒脑静联合果糖、纳洛酮具有协同作用,可提高急性重度酒精中毒患者的恢复质量,缩短苏醒时间,减少继发损害。Objective Xingnaojing joint observation fructose, the effect of naloxone in the treat-ment of acute severe alcoholism.Methods Our hospital in September 2013 September 2014 123 patients with severe cases of acute alcoholism, according to rank admitted into two groups： 61 pa-tients in the singular as a control group given saline＋naloxone combination therapy, double the number 62 patients in the control group, based on the use XNJI, solvent saline and naloxone group to fructose injection, treatment effects were observed.Results Ataxia patients in the obser-vation group recovery time and awake time symptoms were （74.8±20.4）min, （264.5±50.6）min, co-matose patients recovery time and symptoms awake time was （153.4 ±36.7）min, （420.7 ±102.8）min,were shorter than the control group, the total effective rate of 98.38% first aid, the two groups P〈0.05, significant difference. Conclusions Xingnaojing joint fructose, naloxone had a synergistic effect, can improve the quality of recovery in patients with acute severe alcoholism, shorten recov-ery time, reduced secondary damage.

关 键 词：醒脑静 果糖 纳洛酮 急性重度酒精中毒 研究 

分 类 号：R595.6[医药卫生—内科学]