危重患者连续性肾脏替代治疗中用抗感染药物给药方案的研究进展  

Advances of regimen of antimicrobial agents for critically ill patients receiving continuous renal replacement therapy

作　　者：银雪艳[1,2] 陈文瑛[1] 黄桂霞[1] 肖翔林[1] 

机构地区：[1]广州医科大学附属第一医院药学部,广东广州510120 [2]中山大学药学院,广东广州510006

出　　处：《中国医院药学杂志》2015年第7期651-658,共8页Chinese Journal of Hospital Pharmacy

基　　金：广州市属高校科研项目(编号:10A281);广东省医院药学研究项目(编号:2014A11)

摘　　要：接受连续性肾脏替代疗法(continuous renal replacement therapy,CRRT)危重患者抗感染药物剂量的选择是个较为复杂的问题,接受连续性肾脏替代疗法的危重患者其抗感染药物剂量选择目前并没有统一的标准,本文通过查阅国内外与CRRT下抗感染药物剂量相关的文献,发现除少数药物外,其余大部分抗感染药物在患者接受CRRT条件下需要调整剂量。Dose selection of antimicrobial agents for critically ill patients receiving continuous renal replacement therapy（CRRT）is complicated,no recent comprehensive guidelines exist that provide antibiotic dosing recommendations for adult patients receiving CRRT.We reviewed the literatures involving antimicrobial agents frequently used to treat critically ill adult patients receiving CRRT.The literatures at home and abroad about antimicrobial agents dosing in critically ill patients receiving CRRT were searched and reviewed.It is found that except for a few drugs,doses of most antimicrobial agents should be adjusted for critically ill patients receiving CRRT.

关 键 词：连续性肾脏替代疗法 抗感染药物 用药剂量 

分 类 号：R969.3[医药卫生—药理学]