三种炎症指标对颅脑术后发热原因诊断价值的比较  

Diagnostic values of three inflammatory markers in causes of fever after neurosurgical procedures

作　　者：钱佳栋[1] 徐德明[1] 万默各[1] 

机构地区：[1]浙江省嘉兴市第一医院神经外科,314000

出　　处：《中华全科医师杂志》2015年第4期291-293,共3页Chinese Journal of General Practitioners

摘　　要：选择2013年1-12月间91例颅脑术后发热患者,根据是否并发感染分为未感染组（42例）和感染组（49例）,随机选取51例无感染未手术病例为对照组.检验3组的降钙素原（PCT）、CRP和白细胞水平.未感染组与对照组PCT水平差异无统计学意义（P＞0.05）,感染组与未感染组的PCT水平差异有统计学意义（P＜0.01）.未感染组与对照组,感染组与未感染组之间的CRP水平差异有统计学意义（P＜0.01）.白细胞水平在未感染组与对照组间、感染组与未感染组间差异有统计学意义（分别为P＜0.05和＜0.01）.ROC曲线示PCT的灵敏度、特异度均最高.A prospective study was conducted for 91 cases of fever patients after neurosurgical procedures during the period of January-December 2013.They were divided into non-infection （n =42） and infection （n =49） groups according to whether there was infection complication.And another 51 nonsurgical hospitalized patients without fever or infection were selected as control group.The levels of procalcitonin （PCT）,C-reactive protein （CRP） and white blood cell （WBC） were detected respectively.Statistical analysis showed that the level of PCT had no significant difference between non-infection and control groups （P 〉 0.05）.However,it was markedly elevated in infection group than non-infection group （P 〈 0.01）.The level of CRP was significantly different between non-infection and control groups （P 〈 0.01）.And it was the same between infection and non-infection groups.The level of WBC had significant difference between non-infection and control groups （P 〈 0.05） and infection and non-infection groups （P 〈 0.01）.The receiver operating characteristic （ROC） curve showed that either sensitivity or specificity of PCT was the highest.Compared with CRP and WBC,PCT may identify more accurately the causes of fever after neurosurgical procedures.

关 键 词：降钙素原 发热 

分 类 号：R651.1[医药卫生—外科学]