蛴螬化学成分和药理作用的研究进展  

The Research Progress in Chemical Composition and Pharmacological Effects from the Holotrichia Diomphalia Bates

作　　者：刘媛媛[1] 曹蔚[1] 张雅[1] 张蒙[1] 王四旺[1] 

机构地区：[1]第四军医大学药学系天然药物学教研室,陕西西安710032

出　　处：《现代生物医学进展》2015年第12期2375-2377,共3页Progress in Modern Biomedicine

基　　金：陕西省科学技术研究发展计划项目(2012KJXX-21)

摘　　要：蛴螬在中医临床中有着悠久的应用历史,近年来,随着人们对蛴螬的深入研究,化学成分的研究也有了新进展,从蛴螬提取物分离出含氮类化合物、有机酸类化合物和甾体类化合物。在药理学方面,蛴螬提取物具有抗肿瘤、治疗口疮和眼部疾病等多种生物活性,是一种极具研究和开发价值的动物药。现将其近年来的化学成分、药理作用研究进展做一综述,以期为进一步开发利用提供参考资料。Holotrichia diomphalia Bates has a long history of the application in Chinese medicine （TCM）. In recent years, as people in-depth study of the Holotrichia diomphalia Bates, the study of the chemical composition has made new progress. The nitrogen compounds, organic compounds and nonsteroidal compound were isolated from extraction of the Holotrichia diomphalia Bates. In pharmacology, the Holotrichia diomphalia Bates extract has anti-tumor, treatment of aphthous and eye diseases and other bioactive, etc. The Holotrichia diomphalia Bates is a great value in the research and development of animal drugs. This review summarized the recent progress on the research field of chemical composition and Pharmacological effects, so as to provide a reference for the further development and utilization of information.

关 键 词：蛴螬 化学成分 药理作用 

分 类 号：R285[医药卫生—中药学] R965[医药卫生—中医学]