三维超声和核磁共振成像测量先天性膈疝胎儿对侧肺容积相关性研究  

Study on the correlation between three- dimensional ultrasound and MRI in measuring contralateral lung volume of fetuses with congenital diaphragmatic hernia

作　　者：马玉成[1] 纪伟英[1] 何晓俊[1] 马慧静[1] 周燕[1] 

机构地区：[1]湖北省武汉市妇女儿童医疗保健中心,430016

出　　处：《中国妇幼保健》2015年第11期1729-1731,共3页Maternal and Child Health Care of China

基　　金：湖北省武汉市医疗卫生科研项目基金资助项目〔WX14A08〕

摘　　要：目的：探讨三维超声（3D-US）和核磁共振成像（MRI）测量先天性膈疝胎儿对侧肺容积的相关性。方法：2010年1月-2013年2月在该院进行产前检查的55例胎儿,发现先天性膈疝,未合并其他畸形,经随访或尸检得到证实,染色体核型均为正常。24 h内行MRI检查,然后分别采用三维超声自动测量技术（VOCAL）和MRI T2加权多平面测量技术测定对侧肺容积,最后用一元回归分析确定两种方法的相关性。结果：55例胎儿中,左膈疝49例,右膈疝6例,平均孕周29周（范围18-39周）。评估对侧肺容积,3D-US和MRI则有着明显相关性（相关系数r=0.944,P〈0.001）。尽管3D-US测量膈疝胎儿肺容积的平均值要比MRI测量的平均值低22.9%,但是应用两种方法 （实测肺容积与预期肺容积比值：3D-US,0.47;MRI,0.51）无统计学差异。结论：对于单纯膈疝胎儿,3D-US可以准确测量胎儿对侧肺容积。Objective： To explore the correlation between three- dimensional ultrasound（ 3D- US） and MRI in measuring contralateral lung volume of fetuses with congenital diaphragmatic hernia（ CDH）. Methods： From January 2010 to February 2013,55 fetuses with isolated CDH were selected from the hospital after prenatal examination,all the fetuses were diagnosed definitely by follow- up or autopsy,chromosomal karyotypes were normal. MRI was performed with 24 hours after birth,three- dimensional ultrasonic automatic measurement technology and T2- weighted MRI were used to measure contralateral lung volume,the correlation was determined by monadic regressive analysis. Results： Among 55 fetuses,49 fetuses were diagnosed as left CDH and the other 6 fetuses were diagnosed as right CDH; the gestational weeks ranged from 18 to 39 weeks,29 weeks on average. Contralateral lung volume was assessed,there was a significant correlation between 3D- US and MRI（ r = 0. 944,P 〈0. 001）. Although the average value of contralateral lung volume measured by 3D- US was lower than that measured by MRI by 22. 9%,but there was no statistically significant difference between the two methods（ the ratio of actual contralateral lung volume to expected contralateral lung volume： 3D- US： 0. 47; MRI： 0. 51）. Conclusion： For the fetuses with isolated CDH,3D- US can measure contralateral lung volume accurately.

关 键 词：三维超声 磁共振 先天性膈疝 胎儿 

分 类 号：R445.1[医药卫生—影像医学与核医学]