鼻塞式持续呼吸道正压通气治疗高原新生儿频发性呼吸暂停94例临床分析  

Clinical analysis on 97 neonates with frequent apnea treated by nasal continuous positive airway pressure in plateau area

作　　者：石润玲 

机构地区：[1]青海省妇女儿童医院新生儿科,青海西宁810007

出　　处：《中国妇幼保健》2015年第11期1775-1777,共3页Maternal and Child Health Care of China

基　　金：青海省科学技术厅科研项目〔2012-N-521〕

摘　　要：目的:探讨鼻塞式持续气道正压(NCPAP)对高原新生儿频发性呼吸暂停的治疗作用,观察其在治疗新生儿频发性呼吸暂停中的临床效果。方法:对94例在该院NICU住院治疗的新生儿频发性呼吸暂停进行临床疗效观察,所有患儿随机分为两组,治疗组47例患儿常规治疗基础上给予鼻塞式NCPAP,对照组47例患儿给予普通通气(采用鼻导管或头罩吸氧),动态监测两组患儿治疗前、治疗4、12 h后的动脉血气及SPO2并进行比较。结果:两组患儿治疗后12 h血气指标间差异有有统计学意义(P<0.01);治疗组47例患儿应用NCPAP治疗取得满意疗效,病程较对照组明显缩短。结论:鼻塞式NCPAP治疗高原新生儿频发性呼吸暂停,疗效肯定,方法简单,未发现明显的不良反应,是一种无创、安全、有效的通气方式。Objective： To explore the therapeutic effect of nasal continuous positive airway pressure（ n CPAP） on neonates with frequent apnea in plateau area,observe the clinical effect. Methods： Ninety- four neonates with frequent apnea treated in NICU in the hospital were selected and randomly divided into two groups,47 neonates in treatment group were treated by n CPAP based on routine therapy,the other 47 neonates in control group were treated by routine ventilation therapy（ nasal catheter or oxygen inhalation with head masks）. Arterial blood gas indexes and SPO2 values before treatment and at 4 and 12 hours after treatment in the two groups were dynamically monitored and compared. Results： There were statistically significant differences in blood gas indexes at 12 hours after treatment between the two groups（ P 〈0. 01）; in treatment group,the clinical effect of n CPAP is satisfactory,the course of disease was significantly shorter than that in control group. Conclusion： n CPAP has the advantages of high- efficacy and simple operation in treatment of neonates with frequent apnea in plateau area,no obvious adverse reaction was found,which is a noninvasive,safe,and effective ventilation method.

关 键 词：新生儿 呼吸暂停 持续气道正压通气 高原 

分 类 号：R725.6[医药卫生—儿科]