辅助生育中子宫内膜异位症与前置胎盘的相关性  

The correlation between endometriosis and placenta previa in assisted reproductive technology

作　　者：傅秀娟[1] 周勇[2] 金杭美[2] 

机构地区：[1]磐安县人民医院妇产科,浙江金华322300 [2]浙江大学附属妇产科医院妇科,浙江杭州310006

出　　处：《温州医学院学报》2015年第3期197-200,共4页Journal of Wenzhou Medical College

摘　　要：目的:探讨在辅助生育中子宫内膜异位症和前置胎盘的相关性。方法:回顾性分析2008年1月至2012年12月在浙江大学附属妇产科医院接受辅助生殖技术病例,根据纳入标准其中胚胎移植成功且并在单胎28周后分娩者有2060例,有110例发生了前置胎盘。回顾病史分析孕妇年龄、体质量指数、孕次、产次、流产次数、剖宫产史、子宫内膜异位症、排卵障碍、男性不孕等9个指标,分析它们与前置胎盘的相关性。同时对子宫内膜异位症分型与前置胎盘的相关性做进一步研究。结果:2060例观察资料中子宫内膜异位症患者的发生率为15.53%,前置胎盘的发生率为5.34%。110例发生前置胎盘患者中合并子宫内膜异位症患者为69例,对其进行影响因素相关性分析显示子宫内膜异位症OR值为19.7(P=0.001)。子宫内膜异位症类型及严重程度与前置胎盘的发生存在正相关,Kendall相关系数为0.274,Spearman相关系数为0.281,均P<0.001。结论:在辅助生殖中,子宫内膜异位症与前置胎盘存在一定的相关性,且与子宫内膜异位症的病变程度呈正相关。Objective： To investigate placenta previa associated with endometriosis in assisted reproductive technology. Methods： Consecutive 2 060 pregnancies conceived by assisted reproductive technology were recruited between 2008 and 2012 in Women＇s Hospital, School of Medicine, Zhejiang University. The risk of placenta previa after assisted fertilization was analyzed. Relation of nine variables was examined, i.e. maternal age, BMI, gravidity, parity, previous abortion, previous cesarean delivery, endometriosis, ovulatory disorder, and male infertility, to placenta previa by logistic regression analysis. The correlation between endometriosis severity with placenta previa was analyzed by the nonparametric test of Spearman correlation analysis. Results： In 110 women with placenta previa, there were 69 cases complicated with endometriosis. We found that endometriosis（odds ratio=19.7; 95% CI=0.5-300.6） were significantly associated with placenta previa. Endometriosis was more serious more prone to placenta previa（the Kendall correlation coefficient is 0.274, Spearman correlation coefficient is 0.281, all P〈0.001）. Conclusion： Our findings suggest that endometriosis is associated with an increased risk of placenta previa in assisted reproductive technology. The higher degree of endometriosis, the more possible of placenta previa.

关 键 词：子宫内膜异位症 前置胎盘 辅助生育 

分 类 号：R711[医药卫生—妇产科学]