前连合及内囊断层解剖与MRI图像初步对照研究  

Comparative study of the sectional slice of the anterior commissure and the internal capsule with its MRI images

作　　者：王单单[1] 麻雯熠 张晓阳[1] 袁武[1] 李云生[1] 

机构地区：[1]天津医科大学解剖学与组织胚胎学系,天津300070

出　　处：《中国临床解剖学杂志》2015年第2期155-159,共5页Chinese Journal of Clinical Anatomy

基　　金：天津医科大学重点学科项目资助(No.052-200010)

摘　　要：目的探讨内囊与其毗邻结构的断层形态学特征、内囊前肢与前连合之间的空间定位,及其与MRI断层影像的对应关系,为中枢神经系统研究、脑深部刺激治疗精神神经方面的疾病提供可靠的断层解剖学依据。方法利用MRI技术对100例健康成年女性的脑部进行扫描,选取经福尔马林固定的成年女性尸体大脑标本12例,然后经火棉胶包埋技术制成厚为500μm的薄层连续切片,并与MRI图像进行对照研究。结果断层切片可详细阐明内囊及其毗邻结构在不同方位上形态特征,MRI图像不能清晰地辨认内囊与其毗邻结构边界,水平位、冠状位上可观察到前连合连接双侧内囊前肢。结论脑断层解剖切片较MRI图像更能清晰地显示内囊及其毗邻结构的位置关系,为脑深部电刺激内囊治疗某些精神神经疾病提供断层解剖学应用价值。Objective To compare sectional anatomic features of the internal capsule and adjacent structures,the anatomical position of the relationship the anterior limb of internal capsule and the anterior commissure on the horizontal,coronal and sagittal sections with their corresponding MRI images, and to provide a reliable sectional anatomic basis for the study of the central nervous system and deep brain stimulation to treat the mental neurological diseases. Methods The brain of 100 normal persons received MRI scan and image analysis. 12 adult female brain specimens fixed by formalin, were made into serial horizontal、coronal and sagittal slices with the thickness of 500 μm by celloidin embedding techniquefor comparative studyof MRI images and morphologic features. Results The morphological characteristics of the internal capsule and adjacent structures on horizontal, coronal and sagittal sections can be described in detail. The MRI images cannot clearly identify the boundaries of the internal capsule and its adjacent structures. The anterior limb of internal capsule has fiber connections on the horizontal and coronal sections by the anterior commissure. Conclusions Sectional anatomy of brain slices can more clearly demonstrate the positional relationship between the internal capsule and adjacent structures than MRI images on the three directional sections, which can provide valuable data of clinical evaluation of internal capsule in treating mental neurological disease through deep brain stimulation.

关 键 词：女性脑 前连合 内囊 火棉胶 MRI 

分 类 号：R322[医药卫生—人体解剖和组织胚胎学]