益气活血汤联合益肝灵胶囊治疗慢性乙型肝炎肝硬变60例  

60 Cases of Chronic Hepatitis B Cirrhosis Treated with Decoction for Replenishing Qi and Activating Blood Circulation Combined with Yigan Ling Capsule

作　　者：杨昌文 罗小林 

机构地区：[1]宜昌市中心人民医院,湖北宜昌443003

出　　处：《河南中医》2015年第3期543-544,共2页Henan Traditional Chinese Medicine

摘　　要：目的:观察益气活血汤联合益肝灵胶囊治疗慢性乙型肝炎肝硬变的临床疗效。方法:选取2012年9月—2014年3月本院收治的慢性乙型肝炎肝硬变患者120例作为研究对象,随机分为治疗组和对照组各60例。两组患者均采用常规保肝、对症治疗,治疗组给予益气活血汤和益肝灵胶囊治疗,对照组仅给予益肝灵胶囊治疗,两组均以1个月为1个疗程。比较两组患者治疗前后临床症状、体征的变化,检测患者肝功能指标、透明质酸(hyaluronic acid,HA)及血清层黏连蛋白(Serum layer adhesion proteins,LN)。结果:两组患者治疗后,临床症状和体征均有所减轻,但治疗组的症状改善程度明显优于对照组,肝功能、HA及LN的恢复情况明显优于对照组,P均<0.05,均具有统计学意义。治疗组有效率为96.67%,对照组有效率为85.00%,治疗组有效率明显高于对照组,比较差异明显(P<0.05),具有统计学意义。结论:益气活血汤联合益肝灵胶囊治疗慢性乙型肝炎肝硬变疗效显著。Objective： To observe the clinical curative effect of Decoction for Replenishing Qi and Activating Blood Circulation（DRQABC） combined with Yigan Ling Capsule（YGLC） on chronic hepatitis B cirrhosis.Methods： 120 patients with chronic hepatitis B cirrhosis treated in the hospital from Sep.of 2012 to Mar.of 2014 were chosen as the study objects and randomly divided into the treatment group and the control group,with 60 cases in each group.All the patients in both groups accepted routine treatment for protecting liver and symptomatic treatment.The ones in the treatment group were added DRQABC combined with YGLC,while the ones in the control group were only added YGLC.Both groups regarded one month as a treatment course.Then the clinical symptoms,the changes of physical sign of the patients in both groups before and after the treatment were compared; The liver function index,HA and LA were tested.Results： After the treatment,both groups＇ patients＇ clinical symptoms and physical signs alleviated; However,the improved degree of the treatment group was much superior to that of the control group; Its recovery states of liver function,HA and LN were also much superior to those of the control group（all P〈0.05）,and the differences had statistical meaning.The total effective rate of the treatment group（96.67%） was much higher than that（85.00%） of the control group（P〈0.05）; The difference between the two groups was obvious and had statistical meaning.Conclusion： DRQABC combined with YGLC has very good curative effect on chronic hepatitis B cirrhosis.

关 键 词：乙型肝炎肝硬变 益气活血汤 益肝灵胶囊 

分 类 号：R259.752[医药卫生—中西医结合]