Radial glia interact with primary olfactory axons to regulate development of the olfactory bulb  

作　　者：Daniel A.Amaya Jenny A.K.Ekberg James A.St John 

机构地区：[1]Eskitis Institute for Drug Discovery,Griffith University [2]School of Biomedical Sciences,Queensland University of Technology Brisbane

出　　处：《Neural Regeneration Research》2015年第3期374-376,共3页中国神经再生研究（英文版）

基　　金：supported by an Australian Postgraduate Award to D.A

摘　　要：The developing olfactory system - merging of the periph- eral and central nervous systems： The olfactory system is responsible for the sense of smell and is comprised of a complex topographic map that regenerates throughout life. In rodents each olfactory sensory neuron expresses one of N 1,300 odorant receptors with the neurons being distributed mosaically within the epithelium. The axons of the sensory neurons do not maintain near-neighbour relationships and instead project to disparate topographic targets in the olfac- tory bulb within the central nervous system. The develop- ment of the targets relies on the intermingling of the sensory axons with the interneurons, glia and second order neurons of the olfactory bulb. Thus the formation of the olfactory system involves the coordinated integration of the axons of the peripheral olfactory sensory neurons with the cells of the olfactory bulb.The developing olfactory system - merging of the periph- eral and central nervous systems： The olfactory system is responsible for the sense of smell and is comprised of a complex topographic map that regenerates throughout life. In rodents each olfactory sensory neuron expresses one of N 1,300 odorant receptors with the neurons being distributed mosaically within the epithelium. The axons of the sensory neurons do not maintain near-neighbour relationships and instead project to disparate topographic targets in the olfac- tory bulb within the central nervous system. The develop- ment of the targets relies on the intermingling of the sensory axons with the interneurons, glia and second order neurons of the olfactory bulb. Thus the formation of the olfactory system involves the coordinated integration of the axons of the peripheral olfactory sensory neurons with the cells of the olfactory bulb.

关 键 词：Radial glia interact with primary olfactory axons to regulate development of the olfactory bulb 

分 类 号：R339.12[医药卫生—人体生理学]