一种复方过氧化物对透析机消毒性能研究  

Observation on disinfection properties of a compound peroxide disinfectant to dialysis machine

作　　者：陈泰尧[1] 王臻[1] 葛忆琳[1] 田靓[1] 朱仁义[1] 

机构地区：[1]上海市疾病预防控制中心,上海200336

出　　处：《中国消毒学杂志》2015年第2期113-115,共3页Chinese Journal of Disinfection

摘　　要：目的研究一种复方过氧化物消毒液的杀菌效果,评价其用于血液净化设备消毒的可行性。方法采用理化分析和杀菌试验方法 ,对该复方消毒液进行了实验室理化性能分析和杀菌效果观察以及现场消毒试验观察。结果用含165 mg/L过氧乙酸与1 737 mg/L过氧化氢的复方消毒液作用10 min,对悬液内大肠杆菌、金黄色葡萄球菌、铜绿假单胞菌的平均杀灭对数值均大于5.00。用含330 mg/L过氧乙酸和3 474 mg/L过氧化氢的复方消毒液作用45 min,对悬液内枯草杆菌黑色变种芽孢的平均杀灭对数值大于5.00。含过氧乙酸8.25 g/L和过氧化氢86.84 g/L该复方消毒液对单人用透析机内管道循环一个周期后,对人工污染载体的枯草杆菌黑色变种芽孢的平均杀灭对数值为5.62。结论该复方过氧化物消毒液具有良好的杀菌效果,能够满足透析机的消毒要求。Objective To study the germicidal efficacy of a compound disinfectant of peroxide and to evaluate the feasibility for blood purification equipment（ dialysis machine）. Methods Physicochemical analysis and germicidal test were used to observe the physicochemical,germicidal and field disinfection properties of the compound disinfectant of peroxide. Results The killing logarithm values of Escherichia coli,Staphylococcus aureus and Pseudomonas aeruginosa exposed to this compound disinfectant containing 165 mg / L peracetic acid and 1 737 mg / L hydrogen peroxide for 10 min were 5. 00. The killing logarithm value of spores of Bacillus subtilis var. niger exposed to this compound disinfectant containing330 mg / L peracetic acid and 3 474 mg / L hydrogen peroxide for 45 min was 5. 00. The killing logarithm value of spores of Bacillus subtilis var. niger artificially contaminated in single service dialysis machine exposed to this compound disinfectant containing 8. 25 g / L peracetic acid and 86. 84 g / L hydrogen peroxide for one circle was 5. 62. Conclusion The compound disinfectant of peroxide has good germicidal efficacy and meet disinfection requirements of dialysis machine.

关 键 词：复方过氧化物 过氧乙酸 过氧化氢 透析机 消毒 

分 类 号：R187.1[医药卫生—流行病学]