医院感染大肠埃希菌临床分布及耐药性研究  

Clinical distribution and drug resistance of Escherichia coli of nosocomial infection

作　　者：孙云婷[1] 王和[1] 杨怀[2] 

机构地区：[1]贵阳医学院,贵州贵阳550004 [2]贵阳医学院附属人民医院

出　　处：《中国消毒学杂志》2015年第3期244-246,共3页Chinese Journal of Disinfection

基　　金：贵州省科技厅基金资助项目(2273)

摘　　要：目的研究住院患者医院感染大肠埃希菌的分布特点及其耐药性,为感染控制提供依据。方法通过回顾性调查方法,对某医院住院医院感染患者标本分离大肠埃希菌的分布及耐药率进行调查与分析。结果该医院在2012年10月-2013年12月期间从住院感染患者送检标本中共检出大肠埃希菌1 716株,其中医院获得感染占31.24%,社区获得感染占68.76%。医院感染大肠埃希菌的患者主要分布在普外科、肝胆外科和神经外科,社区感染大肠埃希菌的患者主要分布在泌尿外科、儿内科和普外科。临床分离大肠埃希菌对美罗培南和亚胺培南比较敏感,但对头孢唑啉、哌拉西林和氨苄西林的耐药率均>80.00%。结论该医院获得大肠埃希菌感染患者主要分布在普外科,多见于泌尿道感染,美罗培南和亚胺培南为有效治疗药物。Objective To study distribution characteristics and the drug resistance of Escherichia coli（ E. coli） of hospitalized patients with nosocomial infection,so as provide evidence for infection control. Methods Retrospective survey was used to analyze the distribution and resistance rates of E. coli from specimens of hospitalized patients with nosocomial infection. Results 1 716 strains of E. coli were detected out from the specimens of hospitalized patients from Oct 2012 to Dec2013 in this hospital. Among them nosocomial infection accounted for 31. 24% and community infection accounted for68. 76%. Patients with nosocomial infection of E. coli were mainly distributed in general surgery,liver and gallbladder surgery and neurosurgery. Patients with community infection of E. coli were mainly distributed in urology,pediatric and general surgery. The strains of E. coli isolated from clinical was sensitive to meropenem and imipenem. But the resistance rates to cefazolin,piperacillin and ampicillin were more than 80. 00%. Conclusion In this hospital,patients with nosocomial infection of E. coli are mainly distributed in general surgery and the main site is urinary tract. Meropenem and imipenem are effective drugs in the treatment of E. coli infection.

关 键 词：大肠埃希菌 医院感染 社区感染 耐药率 

分 类 号：R378[医药卫生—病原生物学]