硒对奶牛乳腺炎的调节作用及抗炎机制  

Regulation and Anti-Inflammatory Mechanisms of Selenium for Bovine Mastitis

作　　者：张雯[1,2] 张乃生[2] 

机构地区：[1]东北林业大学野生动物资源学院动物医学系,哈尔滨150040 [2]吉林大学动物医学学院,长春130062

出　　处：《动物营养学报》2015年第4期1021-1027,共7页CHINESE JOURNAL OF ANIMAL NUTRITION

基　　金：国家自然科学基金(31272622);中央高校基本科研业务费专项(2572015BAX01)

摘　　要：奶牛乳腺炎在临产和泌乳期奶牛中发病率较高,严重影响乳腺健康和牛奶生产,对世界范围内的奶牛业造成重大经济损失。微量元素硒可降低奶牛乳腺炎的发病率和严重程度。本文从硒与奶牛乳腺炎的关系、硒在炎症中对先天性免疫和获得性免疫的调节作用以及硒对炎症相关信号转导机制的调控等几个方面进行了综述,为通过饲粮补硒以改善奶牛乳腺健康提供理论支持。Bovine mastitis has a high morbidity during the periparturient and lactation period. As a result, mammary gland health and milk performance are affected, thereby causing worldwide economic losses. The trace element selenium （ Se） reduces the morbidity and the severity of mastitis. This article provided an over-view of the most recent researches in the fields of the relationship between the Se and bovine mastitis, the regu-lation of Se in the innate and adaptive immunity, and the regulation of Se on inflammatory response associated signaling pathways. The better understanding on the mechanisms of anti-inflammatory effects of Se can help during the improvement of mammary health of dairy cows.

关 键 词：硒 乳腺炎 免疫 抗炎 信号通路 

分 类 号：S823[农业科学—畜牧学] S856[农业科学—畜牧兽医]