甘油中苯并三氮唑的N-烷基化反应研究  

Research on Chem-Selective N-alkylation of Benzotriazole in Glycerol

作　　者：倪宇翔[1] 许松林[1] 刘硕[1] 杨建国[2,3] 应安国[2,3] 

机构地区：[1]天津大学化工学院,天津300072 [2]台州学院医药化工学院,浙江台州318000 [3]台州学院应用化学研究所,浙江台州318000

出　　处：《高校化学工程学报》2015年第2期341-345,共5页Journal of Chemical Engineering of Chinese Universities

基　　金：国家自然科学基金项目(21106090);浙江省低碳脂肪胺工程技术研究中心开放基金项目(2012E10033)

摘　　要：以甘油为溶剂介绍了一种绿色、高效的苯并三氮唑N-烷基化衍生物的合成方法。该方法简便有效,适用于一系列的烷基卤代物,均能得到相应的N-烷基化产物且收率较高。此外,这种方法对环境无害,产品易分离,且能实现甘油的回收利用。A green and efficient synthesis method of benzotriazole N-alkylated derivatives was introduced using glycerol as a solvent. The method is convenient and efficient, which is suitable for a series of alkyl halides and the corresponding N-alkylated products have excellent yield. Moreover, this method is environment friendly with easy product separation and the glycerol can also be recycled.

关 键 词：N-烷基化 苯并三氮唑 催化 甘油 

分 类 号：O626.22[理学—有机化学]