血压晨峰、动态动脉硬化指数与颈动脉内膜中层厚度相关性分析  

Correlation analysis among morning blood pressure surge,ambulatory arterial stiffness index and carotid artery intima-media thickness

作　　者：刘长萍[1] 卞文明[1] 彭开兵[2] 

机构地区：[1]彭州市人民医院心血管内科,四川成都611930 [2]彭州市人民医院超声科,四川成都611930

出　　处：《心血管康复医学杂志》2015年第2期136-139,共4页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的:探讨血压晨峰、动态动脉硬化指数(AASI)与颈动脉内膜中层厚度(IMT)的相关性。方法:对212例入选高血压病例监测24h动态血压,并行颈动脉超声检查,测量颈总动脉IMT,根据IMT增厚与否分为IMT正常组(84例)和IMT增厚组(128例),计算血压晨峰值及AASI;根据是否存在血压晨峰现象,分为血压晨峰组(120例)和无血压晨峰组(92例),观察血压晨峰、AASI与颈动脉IMT的相关性。结果:与IMT正常组比较,IMT增厚组中AASI[(0.42±0.13)比(0.68±0.14)]及血压晨峰值[(25.94±4.57)mmHg比(36.57±8.41)mmHg]明显升高(P<0.05);与无血压晨峰组比较,血压晨峰组中AASI[(0.43±0.13)比(0.71±0.14)]、IMT[(1.01±0.20)mm比(1.25±0.17)mm]显著增加(P<0.05);直线相关分析结果显示,血压晨峰、AASI与颈动脉IMT呈正相关(r=1.22,0.51,P均<0.05)。结论:血压晨峰和动态动脉硬化指数是颈动脉内膜中层厚度的独立危险因素,且具有预测价值。Objective：To explore the correlation among morning blood pressure surge （MBPS） ,ambulatory arterial stiffness index （AASI） and carotid artery intima‐media thickness （IMT） .Methods ：A total of 212 hypertension pa‐tients received 24h ambulatory blood pressure monitoring and carotid artery ultrasonography to measure carotid IMT .According to IMT thickened or not ,they were divided into normal IMT group （n=84） and thickened IMT group （n = 128） ,then MBPS and AASI were calculated .According to MBPS existed or not ,patients were divided into MBPS group （n = 120） and no MBPS group （n = 92） ,then the correlation among MBPS ,AASI and carotid IMT were observed .Results ： Compared with normal IMT group ,there were significant rise in AASI [ （0.42 ± 0.13） vs .（0.68 ± 0.14）] and MBPS value [ （25.94 ± 4.57） mmHg vs .（36.57 ± 8.41） mmHg] in thickened IMT group , P 〈 0.05 both ;compared with no MBPS group ,there were significant rise in AASI [ （0.43 ± 0.13） vs .（0.71 ± 0.14）] and IMT [（1.01 ± 0.20） mm vs .（1.25 ± 0.17） mm] in MBPS group ,P 〈 0.05 both ;Linear correlation analysis indicated that MBPS and AASI were positively correlated with carotid IMT （ r = 1.22 ,0.51 , P 〈 0.05 both） .Conclusion ： Morning blood pressure surge and ambulatory arterial stiffness index are independent risk factors for carotid artery intima‐media thickness ,and they possess predictive value .

关 键 词：血压监测  便携式 动脉硬化 颈动脉内膜中膜厚度 

分 类 号：R543.509[医药卫生—心血管疾病]