妊娠晚期肝功能异常对妊娠结局的影响  

Influence of liver dysfunction in late pregnancy on pregnant outcome

作　　者：刘颖[1] 曹卉[1] 朱月华[1] 

机构地区：[1]徐州市九七医院妇产科,徐州221000

出　　处：《生殖医学杂志》2015年第4期289-292,共4页Journal of Reproductive Medicine

摘　　要：目的探讨妊娠晚期合并肝功能异常对孕妇妊娠结局的影响。方法分析与比较妊娠晚期肝功能异常孕妇(观察组,50例)与肝功能正常孕妇(对照组,50例)的一般情况、剖宫产率、胎膜早破、早产、产后出血的发生率,孕产妇羊水污染情况及胎儿窘迫情况。结果观察组孕妇的剖宫产率(74.0%)显著高于对照组(36.0%)(P<0.05);在孕产过程中,观察组孕产妇出现胎膜早破、早产、产后出血等危象的发生率均显著大于对照组(P均<0.05);观察组孕产妇羊水出现污染的比例(46.0%)显著高于对照组(18.0%)(P<0.05);同时,观察组孕产妇出现较严重的III度羊水污染的比例(26.0%)显著高于对照组(0.0%)(P<0.05);观察组胎儿窘迫的发生率(24.0%)显著高于对照组(12.0%)(P<0.05)。结论妊娠晚期孕妇肝功能异常会明显影响妊娠结局,应予及时处理,以使此类孕妇安全渡过围产期,保障母婴健康。Objective： To investigate the influence of liver dysfunction in late pregnancy on pregnant outcome. Methods： The clinical data of 50 pregnancy women with liver dysfunction（observation group）and 50 normal pregnant women （control group）in late trimester of pregnancy were analyzed and compared to investigate the effects of liver dysfunction on pregnant outcome. Results： The cesarean rate in observation group was significantly higher than that in control group （74.0% vs. 36.0%）（P〈0.05）. The rates of emergence of premature rupture of membranes,premature delivery,and postpartum hemorrhage were also significantly higher （all P 〈 0.05）. The rate of amniotic fluid pollution in the control group was significantly lower than that in the observation group（18% vs. 46%）（P〈0.05）. The rate of amniotic fluid pollution degree Ⅲ（26.0% vs. 0.0%）and incidence of fetal distress（24% vs. 12%）in the observation group were significantly higher than those in the control group （all P〈0. 05）. Conclusions： The influence of liver dysfunction in late pregnancy on the pregnancy outcome was significant. Proper treatment in time was essential to improve the maternal and child health.

关 键 词：妊娠 肝功能异常 妊娠结局 

分 类 号：R4[医药卫生—临床医学]