呋塞米联合布地奈德雾化吸入在胸科术后患者中的应用  

Application of atomization inhalation with budesonide and furosemide in patients underwent thoracic surgery

作　　者：程春[1] 黄向华[1] 毛清华[1] 王强[1] 何靖康[2] 

机构地区：[1]南通市肿瘤医院胸外科,江苏省226361 [2]苏州大学附属第一医院胸外科

出　　处：《江苏医药》2015年第7期786-787,共2页Jiangsu Medical Journal

摘　　要：目的观察胸科患者术后使用呋塞米联合布地奈德雾化吸入治疗的效果。方法胸科手术患者120例,术后随机均分为两组:A组雾化吸入药物采用布地奈德2mg+呋塞米40mg,加入0.9%氯化钠溶液5ml,雾化吸入,每天2次;B组雾化吸入药物为地塞米松5mg+庆大霉素8万U+α-糜蛋白酶4000U,加入0.9%氯化钠溶液5ml,雾化吸入,每天2次。比较两组雾化吸入效果。结果与B组比较,A组气道分泌物有效清除率高,采用纤维支气管镜吸痰的患者比例少,肺部感染、肺不张及呼吸衰竭等并发症的发生率降低(P<0.05)。结论胸科患者术后采用布地奈德和呋塞米雾化吸入更能有效清除气道分泌物,减少术后肺部并发症的发生。Objective To observe the efficacy of atomization inhalation with budesonide and furosemide in patients underwent thoracic surgery.Methods A total of 120 patients after thoracic surgery was randomly assigned into two groups with 60 cases each.The patients in group A were given atomization inhalation with budesonide 2mg and furosemide 40 mg,and those in group B with dexamethasone 5 mg,gentamicin 80 000 U andα-chymotrypsin 4000 U.The drugs were diluted in normal saline 5ml.Atomization inhalation was performed twice a day.The efficacy was compared between two groups.Results Compared to group B,group A had more complete clearance of airway secretions,less proportion of using fiberoptic bronchoscopy,and lower incidence rates of lung infection,atelectasis and respiratory failure（P〈0.05）.Conclusion Atomization inhalation with budesonide and furosemide is more effective in clearing airway secretions and reducing lung complications after operation in the patients underwent thoracic surgery.

关 键 词：雾化吸入 布地奈德 呋塞米 

分 类 号：R655[医药卫生—外科学]