基于反转恢复实时快速小角度激发成像的心肌T1值量化方法  

Method of myocardial T1 mapping by sampling inversion recovery with real time TurboFLASH

作　　者：高银珠 陈元枝[1] 朱燕杰[2] 钟耀祖[2] 

机构地区：[1]桂林电子科技大学电子工程与自动化学院,广西桂林541004 [2]中国科学院深圳先进技术研究院生物医学与健康工程研究所,广东深圳518055

出　　处：《中国医学影像技术》2015年第4期621-625,共5页Chinese Journal of Medical Imaging Technology

基　　金：四川大学科技支撑计划基金(Y3J0011001)

摘　　要：目的验证反转恢复实时快速小角度激发(IR-rttfl)成像的心肌T1量化方法。方法对仿体、健康志愿者和心肌坏死患者分别进行成像,在3.0T磁场中使用IR-rttfl的扫描方法量化心肌T1值,与MOLLI方法的结果进行对比,并将T1量化的结果用于分析心肌的异常区域。结果 IR-rttfl方法将扫描时间缩短到6s以内,T1量化结果比MOLLI方法更准确,并且能够有效区分患者心肌的异常区域。结论这种方法能够有效抑制心律不齐造成的影响,提高心肌T1量化结果的准确性,对心肌坏死的诊断具有重要意义。Objective To verify the myocardial T1 mapping method by sampling inversion recovery with real time TurboFLASH（IR-rttfl）.Methods IR-rttfl was used in 3.0Tfor phantoms,volunteers and patients with myocardial infarction,and was compared with MOLLI.T1 mapping results were used to analyze the abnormal parts of myocardium.Results IRrttfl method decreased the scan time less than 6seconds,and was more accuracy than MOLLI.IR-rttfl method was able to distinguish the abnormal parts of myocardium.Conclusion This method is an arrhythmia insensitive myocardial T1 mapping technique that improves the accuracy,and it is useful in the diagnosis of myocardial infarction.

关 键 词：心肌 心肌梗死 IR-rttfl方法 MOLLI方法 

分 类 号：R542.2[医药卫生—心血管疾病] R445.2[医药卫生—内科学]