上海市金山区≥50岁者翼状胬肉流行病学调查  

Prevalence and risk factors of pterygium among people aged 50 or above in Jinshan District of Shanghai

作　　者：崔心瀚[1] 徐建江[2] 乐琦骅[2] 项俊[2] 李一敏[2] 葛玲[3] 赵蓉[3] 周晓东[1] 

机构地区：[1]复旦大学附属金山医院,上海201508 [2]复旦大学附属眼耳鼻喉科医院,上海200031 [3]上海市眼病防治中心,200040

出　　处：《中国实用眼科杂志》2015年第4期436-440,共5页Chinese Journal of Practical Ophthalmology

基　　金：上海市卫生局科研课题（20114122）

摘　　要：目的调查上海市金山区农村地区健康体检人群中翼状胬肉的患病率及影响因素，为该地区翼状胬肉的防治提供依据。方法分层整群抽样随机法。在2010年6～8月，对上海市金山区4个村1976名≥50岁农村人口进行调查。调查内容包括问卷调查和详细的眼科检查。对翼状胬肉进行诊断后，计算其患病率和危险因素。结果4个调查地共计检录1506名≥50岁翼状胬肉患者，总受检率为76．21％（1506／1976）。在所有受检对象中，发现翼状胬肉患者341例，患病率为22．64％（341／1506）。应用logistic回归进行分析可知，户外工作年限（OR=I．013，P=0．002）、泪膜破裂时间（OR=0．736，P=0．026）、文化程度（OR=0．793，P=0．05）是翼状胬肉患病的重要危险因素。结论上海市金山区农村人口翼状胬肉患病率高。长期户外工作时间是影响翼状胬肉病情发展的重要危险因素，而泪膜破裂时间的缩短、教育水平的低下与翼状胬肉的发生、发展密切相关。Objective To present the prevalence and risk factors of pterygium among the popu- lation in rural area of Jinshan, Shanghai. Methods A stratified, clustered population-based survey was conducted in Jinshan during June to August, 2010. A total of 1976 individuals of 4 clones aged 50 or above were enrolled. Participants were requested to complete a comprehensive questionnaire and ocular examination. The prevalence and risk factors of pterygium were analyzed. Results A to- tal of 1506 participants completed this study, with a participation rate of 76.21%. Of all the enroll- ments, 341 （22.64%） had pterygium. The logistic regression analysis showed the risk factors of pte- rygium, including longer outdoor working time （OR=1.013, P =0.002）, and poorer education （OR= 0.793, P =0.025）. Moreover, pterygium correlated significantly with shortened TUBT （OR=0.736, P = 0.026）. Conclusions The prevalence of pterygium in people aged 50 years and older is 22.31% in an inshore rural area of Shanghai, China. The high prevalence might be contributed to the environ- ment of Jinshan. The pterygium formation has significant correlation with long years of outdoor work, poor education status and shortened tear break-up time.

关 键 词：翼状胬肉 患病率 流行病学 

分 类 号：R595.7[医药卫生—内科学]