不同手术方法治疗伴鼻中隔偏曲的变应性鼻炎的疗效比较  

Comparison of Effects and Application Value of Different Surgical Methods on Allergic Rhinitis with Nasal Septum Deviation

作　　者：郑立新[1] 

机构地区：[1]武汉市中心医院耳鼻咽喉科,湖北武汉430014

出　　处：《武汉大学学报（医学版）》2015年第3期467-470,共4页Medical Journal of Wuhan University

摘　　要：目的:探讨鼻中隔黏膜下矫正术(NSR)与双下鼻甲低温等离子射频消融术(RFEN)联合鼻中隔黏膜下矫正术在治疗伴鼻中隔偏曲的变应性鼻炎中的价值及疗效。方法:选取2010年1月-2014年2月期间我院收治的76例伴鼻中隔偏曲的变应性鼻炎患者为研究对象,按随机原则分为对照组与观察组各38例,对照组实施单纯鼻中隔黏膜下矫正术,观察组患者实施双下鼻甲低温等离子射频消融术联合鼻中隔黏膜下矫正术。观察比较两组患者术后的鼻腔阻力、远期疗效及稳定性。结果:术前两组患者鼻腔阻力无显著差异(P>0.05),术后3、6个月两组的鼻腔阻力相对于术前均明显降低(P<0.05),但组间比较RFEN+NSR组的鼻腔阻力低于NSR组,差异具统计学意义(P<0.05)。RFEN+NSR组术后6、12个月时的疗效评定均为100.0%,显著高于NSR组的89.5%与78.9%,差异具统计学意义(P<0.05)。术后12个月RFEN+NSR组均无复发,NSR组术后6、12个的复发率分别为5.3%、10.5%,差异具有显著性(P<0.05)。结论:对伴有鼻中隔偏曲的变应性鼻炎患者,联合应用鼻中隔黏膜下矫正术与双下鼻甲低温等离子射频消融术,具有较好的临床疗效,能显著降低鼻腔阻力,改善临床症状,且复发率低,具有稳固的远期疗效,可在临床进行推广。Objective：To discuss the value and effects of nasal septum submucous resection（NSR）and RFEN combined with NSR on the treatment of allergic rhinitis with nasal septum deviation.Methods：A total of 76 patients with allergic rhinitis with nasal septum deviation from January2010 to February 2014 in our hospital were selected and randomly divided into NSR and NSR＋RFEN groups.Nasal resistance,long-term effect,and stability were observed.Results：Before operation,there was no significant difference in nasal resistance（P〈0.05）,but reduced significantly 3and 6months after operation in both groups（P〈0.05）;However,the nasal resistance in RFEN＋NSR group was lower than that in NSR group（P〈0.05）.Effective rate of the RFEN＋NSR group was 100.0%after 6and 12 months,which was significantly higher than 89.5%and78.9% of NSR group（P〈0.05）.After 12 months there was no recurrence in RFEN＋NSR group,while the recurrence of NSR group after 6and 12 months was respectively 5.3% and10.5%（P〈0.05）.Conclusion：For patients with allergic rhinitis with deviated nasal septum,RFEN ＋ NSR shows great clinical effect,which can significantly reduce nasal resistance,improve clinical symptoms,with low recurrence rate and good long-term effects.

关 键 词：变应性鼻炎 鼻中隔偏曲 鼻中隔黏膜下矫正术 双下鼻甲低温等离子射频消融术 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]