Prefrontal cortex and sensory cortices during working memory: quantity and quality  

作　　者：Yixuan Ku Mark Bodner Yong-Di Zhou 

机构地区：[1]Key Laboratory of Brain Functional Genomics, Ministry of Education, Shanghai Key Laboratory of Brain Functional Genomics, Institute of Cognitive Neuroscience, School of Psychology and Cognitive Science, East China Normal University [2]MIND Research Institute [3]Department of Neurosurgery, Johns Hopkins University [4]NYU-ECNU Institute of Brain and Cognitive Science at NYU Shanghai

出　　处：《Neuroscience Bulletin》2015年第2期175-182,共8页神经科学通报（英文版）

基　　金：supported by the National Basic Research Development Program (973 Program) of China (2013CB329501);a Scientific Project of the Science and Technology Commission of Shanghai Municipality, China (11140900600);the Shanghai Committee of Science and Technology (15ZR1410600);the National Natural Science Foundation of China (31100742);funds from the MIND Research Institute, Irvine, CA, USA

摘　　要：The activity in sensory cortices and the prefrontal cortex （PFC） throughout the delay interval of working memory （WM） tasks reflect two aspects of WM-quality and quantity, respectively. The delay activity in sensory cortices is fine-tuned to sensory information and forms the neural basis of the precision of WM storage, while the delay activity in the PFC appears to represent behavioral goals and filters out irrelevant distractions, forming the neural basis of the quantity of task-relevant information in WM. The PFC and sensory cortices interact through different frequency bands of neuronal oscillation （theta, alpha, and gamma） to fulfill goal-directed behaviors.The activity in sensory cortices and the prefrontal cortex （PFC） throughout the delay interval of working memory （WM） tasks reflect two aspects of WM-quality and quantity, respectively. The delay activity in sensory cortices is fine-tuned to sensory information and forms the neural basis of the precision of WM storage, while the delay activity in the PFC appears to represent behavioral goals and filters out irrelevant distractions, forming the neural basis of the quantity of task-relevant information in WM. The PFC and sensory cortices interact through different frequency bands of neuronal oscillation （theta, alpha, and gamma） to fulfill goal-directed behaviors.

关 键 词：working memory prefrontal cortex capacity limit memory precision neuronal oscillations 

分 类 号：R338[医药卫生—人体生理学]