神经移位技术在高位颈脊髓损伤后膈肌功能重建中的应用  

The application of nerve transfer technique for reconstructing diaphragm function in high cervical spinal cord injury

作　　者：张成林[1] 周许辉[1] 贾连顺[1] 袁文[1] 

机构地区：[1]第二军医大学附属长征医院脊柱外科,上海200003

出　　处：《中国矫形外科杂志》2015年第8期718-722,共5页Orthopedic Journal of China

基　　金：国家自然科学基金资助项目(编号:81271354)

摘　　要：神经移位技术最先广泛应用于治疗臂丛神经损伤,主要是指通过将供体神经移位吻合到失神经支配的靶周围神经上,即将结构完整、原始功能可丧失的供体神经移位转接到去神经的受体神经上,供体神经通过轴突再生使得受体神经重塑功能,从而重新支配失神经支配的肌肉。近年来,将起源于颈髓损伤水平以上的神经移位吻合到膈神经上,似乎成为一种颇具潜力的重建高位颈脊髓损伤后膈肌功能的重要手术方式。Neurotization,or nerve transfer,is most commonly used to treat brachial plexus injury by connecting a donor nerve,such as the spinal accessory or intercostal nerves,to a denervated peripheral nerve target.After the transfer,axons grow from the donor nerve into the recipient nerve,innervating previously denervated muscles.In recent years,anastomosis of the donor nerve originating above the level of spinal injury to the spinal accessory nerve seems to be a promising surgery procedure reconstructing diaphragmatic function after cervical spinal cord injury.In this article we make a review of application of nerve transfer in diaphragmatic function reconstruction.

关 键 词：神经移位 高位脊髓损伤 膈肌功能 

分 类 号：R651.2[医药卫生—外科学]