正常肝脏、胰腺、脾脏双源CT碘含量测量的初探  

Determination of iodine content in normal liver,pancreas and spleen using dual energy CT:apreliminary study

作　　者：阚杨杨 任克[1] 谢召勇[1] 李敏[1] 于欣[1] 赵宇[1] 赵丽[1] 徐克[1] 

机构地区：[1]中国医科大学附属第一医院放射科,沈阳110001

出　　处：《放射学实践》2015年第4期308-312,共5页Radiologic Practice

基　　金：辽宁省科学技术计划项目(2012225013)

摘　　要：目的:使用双源CT双能量扫描,探讨正常肝脏、胰腺、脾脏的碘含量特征,建立正常肝脏、胰腺、脾脏的碘含量参考值。方法:对54例非器质性疾病患者行双源CT双能量双期增强扫描。使用Siemens Dual Energy-Liver VNC图像处理软件对动脉晚期、门静脉期0.7mm图像进行分析处理。测量肝脏、胰腺(胰头、胰体、胰尾)、脾脏及腹主动脉(腹腔干开口的上一层面)的含碘值,并计算标化含碘值(nIC)。结果:正常肝脏在动脉晚期和门脉期的nIC值分别为0.10±0.09和0.40±0.09;正常胰腺各部位在动脉晚期的nIC值分别为0.29±0.32(胰头)、0.29±0.31(胰体)和0.28±0.35(胰尾),在门脉期分别为0.49±0.21(胰头)、0.46±0.17(胰体)和0.46±0.16(胰尾);正常脾脏在门脉期的nIC值为0.02±0.05。不同年龄、不同性别组间正常肝脏、胰腺和脾脏nIC值的差异均无统计学意义(P>0.05);胰腺不同部位nIC值的差异无统计学意义(P>0.05);不同扫描期相肝脏nIC值的差异有统计学意义(P<0.05)。结论:双源CT扫描可获得正常肝脏、胰腺、脾脏的碘含量,可为肝脏、胰腺及脾脏疾病的诊断提供参考。Objective：To analyze the characteristics of iodine distribution in normal liver,pancreas and spleen,and to establish the normal reference value of iodine content in these organs by using dual energy CT.Methods：54 adults without organic disease were recruited and underwent dual energy CT examination.The Siemens Dual Energy software was used to analyze the iodine content of normal liver,pancreas and spleen in late arterial and portal venous phase.The iodine concentra-tion in aorta,liver,pancreas and spleen were measured on the iodine-based material-decomposition images,and were further normalized （nIC）and compared.Results：The nIC of liver in late arterial and portal venous phase was 0.10 ±0.09 and 0.40±0.09,respectively;the nIC in head,body,and tail of pancreas was 0.29±0.32,0.29±0.31 and 0.28±0.3 in late ar-terial phase,and 0.49±0.21,0.46±0.17 and 0.46±0.16 in portal venous phase;the nIC of spleen in portal venous phase was 0.02±0.05.There were no significant differences of nIC in liver,pancreas （head,body,tail）and spleen between gender and different age groups （P〉0.05）.The nICs of liver in the two phases were statistically different （P〈0.05）.There were no significant differences among the nICs of pancreatic head,body and tail （P〈0.05）.Conclusion：The information of io-dine content of liver,pancreas and spleen can be provided by dual energy CT scan,which is helpful for the diagnosis of le-sions in these organs.

关 键 词：肝脏 胰腺 脾脏 双能量成像 双源CT 碘含量 

分 类 号：R816.5[医药卫生—放射医学]